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Otolaryngol Head Neck Surg ; 135(4): 561-4, 2006 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-17011417

RESUMO

OBJECTIVE: This study was undertaken to compare the effects of radiofrequency and injection snoreplasty on the histological structure of the soft palate in an animal model. STUDY DESIGN AND SETTING: This is a blinded, controlled histologic evaluation of rat soft palates that underwent separate palatal interventions. Fifty rats were divided into 5 groups of 10 rats (Group 1 = injection snoreplasty [IS], Group 2 = IS + steroid, Group 3 = saline injection, Group 4 = radiofrequency ablation [RFA], and Group 5 = no intervention). The animals were sacrificed after 24 hours, 1 week, 3 weeks, and 5 weeks. Then the soft palates were subjected to histological analysis. RESULTS: Histological analysis demonstrated normal remucosalization in all specimens, with fibrosis increased in Group 1. Interstitial edema was minimal in Group 2. Keratinization was most apparent in Group 4. CONCLUSION: Radiofrequency and injection snoreplasty stiffen the rat soft palate compared with controls.


Assuntos
Ablação por Cateter , Palato Mole/efeitos dos fármacos , Palato Mole/cirurgia , Polietilenoglicóis/administração & dosagem , Soluções Esclerosantes/administração & dosagem , Escleroterapia , Ronco/patologia , Ronco/terapia , Animais , Injeções Intralesionais , Palato Mole/anatomia & histologia , Polidocanol , Ratos , Ratos Sprague-Dawley
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