Detalhe da pesquisa
1.
A phase Ib study of adavosertib, a selective Wee1 inhibitor, in patients with locally advanced or metastatic solid tumors.
Invest New Drugs
; 41(3): 493-502, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37171722
2.
DKK1 is a predictive biomarker for response to DKN-01: Results of a phase 2 basket study in women with recurrent endometrial carcinoma.
Gynecol Oncol
; 172: 82-91, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37001446
3.
Phase I study of liposomal irinotecan in patients with metastatic breast cancer: findings from the expansion phase.
Breast Cancer Res Treat
; 185(3): 759-771, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-33201358
4.
Phase 1 study of MRX34, a liposomal miR-34a mimic, in patients with advanced solid tumours.
Br J Cancer
; 122(11): 1630-1637, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32238921
5.
Phase 1 study of TTC-352 in patients with metastatic breast cancer progressing on endocrine and CDK4/6 inhibitor therapy.
Breast Cancer Res Treat
; 183(3): 617-627, 2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-32696319
6.
A first-in-human, phase 1, dose-escalation study of ABBV-176, an antibody-drug conjugate targeting the prolactin receptor, in patients with advanced solid tumors.
Invest New Drugs
; 38(6): 1815-1825, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32524319
7.
Phase I study of imalumab (BAX69), a fully human recombinant antioxidized macrophage migration inhibitory factor antibody in advanced solid tumours.
Br J Clin Pharmacol
; 86(9): 1836-1848, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32207164
8.
A phase 1, open-label, dose-escalation trial of oral TSR-011 in patients with advanced solid tumours and lymphomas.
Br J Cancer
; 121(2): 131-138, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31217479
9.
Update on Precision Medicine in Breast Cancer.
Cancer Treat Res
; 178: 45-80, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31209841
10.
Phase I study of MRX34, a liposomal miR-34a mimic, administered twice weekly in patients with advanced solid tumors.
Invest New Drugs
; 35(2): 180-188, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27917453
11.
AKT in cancer: new molecular insights and advances in drug development.
Br J Clin Pharmacol
; 82(4): 943-56, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27232857
12.
A pilot study utilizing multi-omic molecular profiling to find potential targets and select individualized treatments for patients with previously treated metastatic breast cancer.
Breast Cancer Res Treat
; 147(3): 579-88, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25209003
13.
Pretherapy Ferumoxytol-enhanced MRI to Predict Response to Liposomal Irinotecan in Metastatic Breast Cancer.
Radiol Imaging Cancer
; 5(2): e220022, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36734848
14.
Dantrolene sodium for the treatment of aldesleukin-induced rigors in a melanoma patient.
Ann Pharmacother
; 46(5): e11, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22510667
15.
Overcoming Taxane Resistance: Preclinical and Phase 1 Studies of Relacorilant, a Selective Glucocorticoid Receptor Modulator, with Nab-Paclitaxel in Solid Tumors.
Clin Cancer Res
; 28(15): 3214-3224, 2022 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35583817
16.
IOLite: phase 1b trial of doublet/triplet combinations of dostarlimab with niraparib, carboplatin-paclitaxel, with or without bevacizumab in patients with advanced cancer.
J Immunother Cancer
; 10(3)2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35332062
17.
Safety, antitumor activity, and pharmacokinetics of dostarlimab, an anti-PD-1, in patients with advanced solid tumors: a dose-escalation phase 1 trial.
Cancer Chemother Pharmacol
; 89(1): 93-103, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34750637
18.
Multiple Gastrointestinal Symptoms Are Associated With Chemotherapy-Induced Nausea in Patients With Breast Cancer.
Cancer Nurs
; 45(3): 181-189, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-34183520
19.
First-in-Human Study of PF-06647020 (Cofetuzumab Pelidotin), an Antibody-Drug Conjugate Targeting Protein Tyrosine Kinase 7, in Advanced Solid Tumors.
Clin Cancer Res
; 27(16): 4511-4520, 2021 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34083232
20.
Effect of Capivasertib in Patients With an AKT1 E17K-Mutated Tumor: NCI-MATCH Subprotocol EAY131-Y Nonrandomized Trial.
JAMA Oncol
; 7(2): 271-278, 2021 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33377972