Detalhe da pesquisa
1.
SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.
Proc Natl Acad Sci U S A
; 118(6)2021 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33536335
2.
Replication-dependent cytotoxicity and Spartan-mediated repair of trapped PARP1-DNA complexes.
Nucleic Acids Res
; 49(18): 10493-10506, 2021 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34551432
3.
Topoisomerase I-driven repair of UV-induced damage in NER-deficient cells.
Proc Natl Acad Sci U S A
; 117(25): 14412-14420, 2020 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32513688
4.
BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II-DNA complexes.
Proc Natl Acad Sci U S A
; 115(45): E10642-E10651, 2018 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30352856
5.
TOP3A coupling with replication forks and repair of TOP3A cleavage complexes.
Cell Cycle
; 23(2): 115-130, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38341866
6.
Replication-associated formation and repair of human topoisomerase IIIα cleavage complexes.
Nat Commun
; 14(1): 1925, 2023 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37024461
7.
The TDRD3-USP9X complex and MIB1 regulate TOP3B homeostasis and prevent deleterious TOP3B cleavage complexes.
Nat Commun
; 14(1): 7524, 2023 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37980342
8.
ATR inhibition augments the efficacy of lurbinectedin in small-cell lung cancer.
EMBO Mol Med
; 15(8): e17313, 2023 08 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37491889
9.
A high-throughput 384-well CometChip platform reveals a role for 3-methyladenine in the cellular response to etoposide-induced DNA damage.
NAR Genom Bioinform
; 4(3): lqac065, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-36110898
10.
Resolution of R-loops by topoisomerase III-ß (TOP3B) in coordination with the DEAD-box helicase DDX5.
Cell Rep
; 40(2): 111067, 2022 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35830799
11.
TOP1-DNA Trapping by Exatecan and Combination Therapy with ATR Inhibitor.
Mol Cancer Ther
; 21(7): 1090-1102, 2022 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35439320
12.
Novel and Highly Potent ATR Inhibitor M4344 Kills Cancer Cells With Replication Stress, and Enhances the Chemotherapeutic Activity of Widely Used DNA Damaging Agents.
Mol Cancer Ther
; 20(8): 1431-1441, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34045232
13.
Debulking of topoisomerase DNA-protein crosslinks (TOP-DPC) by the proteasome, non-proteasomal and non-proteolytic pathways.
DNA Repair (Amst)
; 94: 102926, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32674013
14.
Enhancing the sensitivity of the thymidine kinase assay by using DNA repair-deficient human TK6 cells.
Environ Mol Mutagen
; 61(6): 602-610, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32243652
15.
Excision repair of topoisomerase DNA-protein crosslinks (TOP-DPC).
DNA Repair (Amst)
; 89: 102837, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32200233
16.
UBC13-Mediated Ubiquitin Signaling Promotes Removal of Blocking Adducts from DNA Double-Strand Breaks.
iScience
; 23(4): 101027, 2020 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32283528
17.
Author Correction: ATR inhibition augments the efficacy of lurbinectedin in small-cell lung cancer.
EMBO Mol Med
; 16(3): 664, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38366163
18.
Differential micronucleus frequency in isogenic human cells deficient in DNA repair pathways is a valuable indicator for evaluating genotoxic agents and their genotoxic mechanisms.
Environ Mol Mutagen
; 59(6): 529-538, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29761828