Detalhe da pesquisa
1.
Stereospecific interactions between histidine and monoclonal antibodies.
Biotechnol Bioeng
; 116(10): 2632-2639, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31286487
2.
Orthogonal high-throughput thermal scanning method for rank ordering protein formulations.
AAPS PharmSciTech
; 14(4): 1360-6, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24002823
3.
Determination of ICH-Q3D Elemental Impurity Leachables in Glass Vials by Inductively Coupled Plasma Mass Spectrometry.
PDA J Pharm Sci Technol
; 77(3): 197-210, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36241213
4.
Computational design and biophysical characterization of aggregation-resistant point mutations for γD crystallin illustrate a balance of conformational stability and intrinsic aggregation propensity.
Biochemistry
; 50(5): 628-39, 2011 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21184609
5.
Reexamining protein-protein and protein-solvent interactions from Kirkwood-Buff analysis of light scattering in multi-component solutions.
J Chem Phys
; 134(22): 225103, 2011 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21682538
6.
Macromolecule-induced assembly of coiled-coils in alternating multiblock polymers.
Biomacromolecules
; 10(10): 2740-9, 2009 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-19743840
7.
Chemical and physical instabilities in manufacturing and storage of therapeutic proteins.
Curr Opin Biotechnol
; 60: 159-167, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30861476
8.
Separation, Characterization and Discriminant Analysis of Subvisible Particles in Biologics Formulations.
Curr Pharm Biotechnol
; 20(3): 232-244, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30767738
9.
Predicting High-Concentration Interactions of Monoclonal Antibody Solutions: Comparison of Theoretical Approaches for Strongly Attractive Versus Repulsive Conditions.
J Phys Chem B
; 123(27): 5709-5720, 2019 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31241333
10.
Developing Biotherapeutics in the New Decade.
J Pharm Innov
; 15(2)2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-32582399
11.
Reduction of the C191-C220 disulfide of α-chymotrypsinogen A reduces nucleation barriers for aggregation.
Biophys Chem
; 185: 79-87, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24374388
12.
Coarse-grained model for colloidal protein interactions, B(22), and protein cluster formation.
J Phys Chem B
; 117(50): 16013-28, 2013 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-24289039
13.
Size-exclusion chromatography with multi-angle light scattering for elucidating protein aggregation mechanisms.
Methods Mol Biol
; 899: 403-23, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22735967
14.
Relating particle formation to salt- and pH-dependent phase separation of non-native aggregates of alpha-chymotrypsinogen A.
J Pharm Sci
; 101(10): 3651-60, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22806414
15.
Aggregation and pH-temperature phase behavior for aggregates of an IgG2 antibody.
J Pharm Sci
; 101(5): 1678-87, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22246657
16.
Predicting solution aggregation rates for therapeutic proteins: approaches and challenges.
Int J Pharm
; 418(2): 318-33, 2011 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21497188
17.
Comparative effects of pH and ionic strength on protein-protein interactions, unfolding, and aggregation for IgG1 antibodies.
J Pharm Sci
; 99(12): 4830-48, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20821389