Detalhe da pesquisa
1.
Spatial Transcriptomics and In Situ Sequencing to Study Alzheimer's Disease.
Cell
; 182(4): 976-991.e19, 2020 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32702314
2.
Alzheimer's Disease Mechanisms and Emerging Roads to Novel Therapeutics.
Annu Rev Neurosci
; 39: 57-79, 2016 07 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27050320
3.
A genetic link between risk for Alzheimer's disease and severe COVID-19 outcomes via the OAS1 gene.
Brain
; 144(12): 3727-3741, 2021 12 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-34619763
4.
N-Terminal Extensions Retard Aß42 Fibril Formation but Allow Cross-Seeding and Coaggregation with Aß42.
J Am Chem Soc
; 137(46): 14673-85, 2015 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26535489
5.
On the identification of low allele frequency mosaic mutations in the brains of Alzheimer's disease patients.
Alzheimers Dement
; 11(11): 1265-76, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25937274
6.
Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease.
Nat Neurosci
; 26(3): 406-415, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36747024
7.
Single-Nucleus RNA-Seq Is Not Suitable for Detection of Microglial Activation Genes in Humans.
Cell Rep
; 32(13): 108189, 2020 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32997994
8.
An NSAID-like compound, FT-9, preferentially inhibits gamma-secretase cleavage of the amyloid precursor protein compared to its effect on amyloid precursor-like protein 1.
Biochemistry
; 48(46): 10894-904, 2009 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-19821615
9.
Single-Cell Quantification of mRNA Expression in The Human Brain.
Sci Rep
; 9(1): 12353, 2019 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31451701
10.
The Major Risk Factors for Alzheimer's Disease: Age, Sex, and Genes Modulate the Microglia Response to Aß Plaques.
Cell Rep
; 27(4): 1293-1306.e6, 2019 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31018141
11.
Stem-cell-derived human microglia transplanted in mouse brain to study human disease.
Nat Neurosci
; 22(12): 2111-2116, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31659342
12.
A self-organizing miR-132/Ctbp2 circuit regulates bimodal notch signals and glial progenitor fate choice during spinal cord maturation.
Dev Cell
; 30(4): 423-36, 2014 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-25132384
13.
Reduced expression of hsa-miR-27a-3p in CSF of patients with Alzheimer disease.
Neurology
; 81(24): 2103-6, 2013 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24212398
14.
Alzheimer brain-derived amyloid ß-protein impairs synaptic remodeling and memory consolidation.
Neurobiol Aging
; 34(5): 1315-27, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23182244
15.
beta-Secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins.
FEBS J
; 277(6): 1503-18, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20163459