Detalhe da pesquisa
1.
Cytotoxic Activity, Topoisomerase I Inhibition and In Silico Studies of New Sesquiterpene-aryl Ester Derivatives of (-) Drimenol.
Molecules
; 28(9)2023 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37175368
2.
Phenoxy- and Phenylamino-Heterocyclic Quinones: Synthesis and Preliminary Anti-Pancreatic Cancer Activity.
Chem Biodivers
; 19(6): e202101036, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35581163
3.
A New Smoothened Antagonist Bearing the Purine Scaffold Shows Antitumour Activity In Vitro and In Vivo.
Int J Mol Sci
; 22(16)2021 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34445078
4.
New 2,6,9-trisubstituted purine derivatives as Bcr-Abl and Btk inhibitors and as promising agents against leukemia.
Bioorg Chem
; 94: 103361, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31699386
5.
New aryloxy-quinone derivatives with promising activity on Trypanosoma cruzi.
Arch Pharm (Weinheim)
; 353(1): e1900213, 2020 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-31709599
6.
Nature-inspired pyrrolo[2,3-d]pyrimidines targeting the histamine H3 receptor.
Bioorg Med Chem
; 27(14): 3194-3200, 2019 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31176569
7.
New lead elements for histamine H3 receptor ligands in the pyrrolo[2,3-d]pyrimidine class.
Bioorg Med Chem Lett
; 28(17): 2890-2893, 2018 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30025902
8.
(-)-Shikimic Acid as a Chiral Building Block for the Synthesis of New Cytotoxic 6-Aza-Analogues of Angucyclinones.
Molecules
; 23(6)2018 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29895756
9.
Fluorescence properties of aurone derivatives: an experimental and theoretical study with some preliminary biological applications.
Photochem Photobiol Sci
; 16(8): 1268-1276, 2017 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28636041
10.
Gramicidin conformational changes during riboflavin photosensitized oxidation in solution and the effect of N-methylation of tryptophan residues.
Photochem Photobiol Sci
; 14(4): 748-56, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25611022
11.
Synthesis and pharmacophore modelling of 2,6,9-trisubstituted purine derivatives and their potential role as apoptosis-inducing agents in cancer cell lines.
Molecules
; 20(4): 6808-26, 2015 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25884555
12.
Synthesis and biological characterization of new aryloxyindole-4,9-diones as potent trypanosomicidal agents.
Bioorg Med Chem Lett
; 24(16): 3919-22, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25008454
13.
2-Phenylaminonaphthoquinones and related compounds: synthesis, trypanocidal and cytotoxic activities.
Bioorg Med Chem
; 22(17): 4609-20, 2014 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25127463
14.
In vitro and In vivo Biological Activity of Two Aryloxy-naphthoquinones in Mice Infected with Trypanosoma cruzi Strains.
Med Chem
; 2024 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38757318
15.
New Inhibitors of Bcr-Abl Based on 2,6,9-Trisubstituted Purine Scaffold Elicit Cytotoxicity in Chronic Myeloid Leukemia-Derived Cell Lines Sensitive and Resistant to TKIs.
Pharmaceutics
; 16(5)2024 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38794311
16.
New short strategy for the synthesis of the dibenz[b,f]oxepin scaffold.
Molecules
; 18(12): 14797-806, 2013 Nov 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-24352054
17.
Mode of action of p-quinone derivatives with trypanocidal activity studied by experimental and in silico models.
Eur J Med Chem
; 246: 114926, 2023 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36508970
18.
Pharmacological insights emerging from the characterization of a large collection of synthetic cannabinoid receptor agonists designer drugs.
Biomed Pharmacother
; 164: 114934, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37236027
19.
Exploring the Effect of Halogenation in a Series of Potent and Selective A2B Adenosine Receptor Antagonists.
J Med Chem
; 66(1): 890-912, 2023 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36517209
20.
Efficient indium-mediated dehalogenation of aromatics in ionic liquid media.
Molecules
; 18(1): 398-407, 2012 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23275048