Detalhe da pesquisa
1.
The prototype HIV-1 maturation inhibitor, bevirimat, binds to the CA-SP1 cleavage site in immature Gag particles.
Retrovirology
; 8: 101, 2011 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-22151792
2.
A single polymorphism in HIV-1 subtype C SP1 is sufficient to confer natural resistance to the maturation inhibitor bevirimat.
Antimicrob Agents Chemother
; 55(7): 3324-9, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21502630
3.
Polymorphisms in Gag spacer peptide 1 confer varying levels of resistance to the HIV- 1 maturation inhibitor bevirimat.
Retrovirology
; 7: 36, 2010 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-20406463
4.
Impact of human immunodeficiency virus type 1 resistance to protease inhibitors on evolution of resistance to the maturation inhibitor bevirimat (PA-457).
J Virol
; 83(10): 4884-94, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19279107
5.
Complementation of diverse HIV-1 Env defects through cooperative subunit interactions: a general property of the functional trimer.
Retrovirology
; 6: 75, 2009 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-19671162
6.
Susceptibility of human immunodeficiency virus type 1 to the maturation inhibitor bevirimat is modulated by baseline polymorphisms in Gag spacer peptide 1.
Antimicrob Agents Chemother
; 53(5): 2185-8, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19223634
7.
Highlights from the Fourth Biennial Strategies for an HIV Cure Meeting, 10-12 October 2018, Bethesda, MD, USA.
J Virus Erad
; 5(1): 50-59, 2019 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30800428
8.
Recommendations for analytical antiretroviral treatment interruptions in HIV research trials-report of a consensus meeting.
Lancet HIV
; 6(4): e259-e268, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30885693
9.
Bevirimat: a novel maturation inhibitor for the treatment of HIV-1 infection.
Antivir Chem Chemother
; 19(3): 107-13, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-19024627
10.
Maturation inhibitors: a new therapeutic class targets the virus structure.
AIDS Rev
; 9(3): 162-72, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17982941
11.
Highlights from the 8th International Workshop on HIV Persistence during Therapy, 12-15 December 2017, Miami, FL, USA.
J Virus Erad
; 4(2): 132-142, 2018 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29682308
12.
Highlights from the Third Biennial Strategies for an HIV Cure Meeting: 14-16 November 2016, Bethesda, MD, USA.
J Virus Erad
; 3(1): 69-76, 2017 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28275462
13.
Highlights from the Seventh International Workshop on HIV Persistence during Therapy, 8-11 December 2015, Miami, Florida, USA.
J Virus Erad
; 2(1): 57-65, 2016 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27482437
14.
Highlights of the 9th edition of the Conference on HIV Persistence During Therapy, 10-13 December 2019, Miami, USA.
J Virus Erad
; 6(2): 85-95, 2020 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32405427
15.
Elevated temperature triggers human respiratory syncytial virus F protein six-helix bundle formation.
Virology
; 396(2): 226-37, 2010 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-19922971
16.
Virus maturation as a new HIV-1 therapeutic target.
Expert Opin Ther Targets
; 13(8): 895-908, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19534569
17.
Anti-AIDS agents. 78. Design, synthesis, metabolic stability assessment, and antiviral evaluation of novel betulinic acid derivatives as potent anti-human immunodeficiency virus (HIV) agents.
J Med Chem
; 52(10): 3248-58, 2009 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-19388685
18.
Phase I and II study of the safety, virologic effect, and pharmacokinetics/pharmacodynamics of single-dose 3-o-(3',3'-dimethylsuccinyl)betulinic acid (bevirimat) against human immunodeficiency virus infection.
Antimicrob Agents Chemother
; 51(10): 3574-81, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17638699
19.
3-O-(3',3'-dimethysuccinyl) betulinic acid inhibits maturation of the human immunodeficiency virus type 1 Gag precursor assembled in vitro.
J Virol
; 80(12): 5716-22, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16731910
20.
In vitro resistance to the human immunodeficiency virus type 1 maturation inhibitor PA-457 (Bevirimat).
J Virol
; 80(22): 10957-71, 2006 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16956950