Detalhe da pesquisa
1.
Anatomy of an extensively drug-resistant Klebsiella pneumoniae outbreak in Tuscany, Italy.
Proc Natl Acad Sci U S A
; 118(48)2021 11 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34819373
2.
The impact of counterions in biological activity: case study of antibacterial alkylguanidino ureas.
Mol Divers
; 27(3): 1489-1499, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-36036302
3.
Benzenesulfonamide derivatives as Vibrio cholerae carbonic anhydrases inhibitors: a computational-aided insight in the structural rigidity-activity relationships.
J Enzyme Inhib Med Chem
; 38(1): 2201402, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37073528
4.
Peptaibol Analogs Show Potent Antibacterial Activity against Multidrug Resistant Opportunistic Pathogens.
Int J Mol Sci
; 24(9)2023 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37175704
5.
Lunaemycins, New Cyclic Hexapeptide Antibiotics from the Cave Moonmilk-Dweller Streptomyces lunaelactis MM109T.
Int J Mol Sci
; 24(2)2023 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36674628
6.
1,2,4-Triazole-3-thione analogues with an arylakyl group at position 4 as metallo-ß-lactamase inhibitors.
Bioorg Med Chem
; 72: 116964, 2022 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36030663
7.
4-Alkyl-1,2,4-triazole-3-thione analogues as metallo-ß-lactamase inhibitors.
Bioorg Chem
; 113: 105024, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34116340
8.
An update on antibacterial AlkylGuanidino Ureas: Design of new derivatives, synergism with colistin and data analysis of the whole library.
Eur J Med Chem
; 270: 116362, 2024 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38574637
9.
4-Trifluoromethyl bithiazoles as broad-spectrum antimicrobial agents for virus-related bacterial infections or co-infections.
RSC Med Chem
; 15(5): 1589-1600, 2024 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38784463
10.
Nucleoside Derivatives of 2,6-Diaminopurine Antivirals: Base-Modified Nucleosides with Broad-Spectrum Antimicrobial Properties.
ChemMedChem
; 18(16): e202300200, 2023 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37221137
11.
Zidovudine-ß-Lactam Pronucleoside Strategy for Selective Delivery into Gram-Negative Bacteria Triggered by ß-Lactamases.
ACS Infect Dis
; 9(8): 1546-1557, 2023 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37439673
12.
Structure-Based Optimization of 1,2,4-Triazole-3-Thione Derivatives: Improving Inhibition of NDM-/VIM-Type Metallo-ß-Lactamases and Synergistic Activity on Resistant Bacteria.
Pharmaceuticals (Basel)
; 16(12)2023 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38139809
13.
Optimization of Pyrazole Compounds as Antibiotic Adjuvants Active against Colistin- and Carbapenem-Resistant Acinetobacter baumannii.
Antibiotics (Basel)
; 11(12)2022 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36551489
14.
Antibacterial alkylguanidino ureas: Molecular simplification approach, searching for membrane-based MoA.
Eur J Med Chem
; 231: 114158, 2022 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35168113
15.
Towards Innovative Antibacterial Correctors for Cystic Fibrosis Targeting the Lung Microbiome with a Multifunctional Effect.
ChemMedChem
; 17(17): e202200277, 2022 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35638249
16.
1,2,4-Triazole-3-Thione Analogues with a 2-Ethylbenzoic Acid at Position 4 as VIM-type Metallo-ß-Lactamase Inhibitors.
ChemMedChem
; 17(7): e202100699, 2022 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35050549
17.
Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-ß-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates.
J Med Chem
; 65(24): 16392-16419, 2022 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36450011
18.
1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-ß-lactamase inhibitors with re-sensitization activity.
Eur J Med Chem
; 226: 113873, 2021 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34626878
19.
Screen of Unfocused Libraries Identified Compounds with Direct or Synergistic Antibacterial Activity.
ACS Med Chem Lett
; 11(5): 899-905, 2020 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32435403
20.
Isonitrile-Based Multicomponent Synthesis of ß-Amino Boronic Acids as ß-Lactamase Inhibitors.
Antibiotics (Basel)
; 9(5)2020 May 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32408714