Detalhe da pesquisa
1.
Titin's cardiac-specific N2B element is critical to mechanotransduction during volume overload of the heart.
J Mol Cell Cardiol
; 191: 40-49, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38604403
2.
A missense variant in the titin gene in Doberman pinscher dogs with familial dilated cardiomyopathy and sudden cardiac death.
Hum Genet
; 138(5): 515-524, 2019 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-30715562
3.
Experimentally Increasing the Compliance of Titin Through RNA Binding Motif-20 (RBM20) Inhibition Improves Diastolic Function In a Mouse Model of Heart Failure With Preserved Ejection Fraction.
Circulation
; 134(15): 1085-1099, 2016 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27630136
4.
Deleting titin's I-band/A-band junction reveals critical roles for titin in biomechanical sensing and cardiac function.
Proc Natl Acad Sci U S A
; 111(40): 14589-94, 2014 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25246556
5.
Reduced passive force in skeletal muscles lacking protein arginylation.
Am J Physiol Cell Physiol
; 310(2): C127-35, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26511365
6.
Sex dimorphisms of crossbridge cycling kinetics in transgenic hypertrophic cardiomyopathy mice.
Am J Physiol Heart Circ Physiol
; 311(1): H125-36, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27199124
7.
Increased myocardial stiffness due to cardiac titin isoform switching in a mouse model of volume overload limits eccentric remodeling.
J Mol Cell Cardiol
; 79: 104-14, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25450617
8.
Experimentally increasing titin compliance in a novel mouse model attenuates the Frank-Starling mechanism but has a beneficial effect on diastole.
Circulation
; 129(19): 1924-36, 2014 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24599837
9.
Shortening of the elastic tandem immunoglobulin segment of titin leads to diastolic dysfunction.
Circulation
; 128(1): 19-28, 2013 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23709671
10.
Right ventricular diastolic impairment in patients with pulmonary arterial hypertension.
Circulation
; 128(18): 2016-25, 1-10, 2013 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-24056688
11.
Effect of exercise training on post-translational and post-transcriptional regulation of titin stiffness in striated muscle of wild type and IG KO mice.
Arch Biochem Biophys
; 552-553: 100-7, 2014 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24603287
12.
The multifunctional Ca(2+)/calmodulin-dependent protein kinase II delta (CaMKIIδ) phosphorylates cardiac titin's spring elements.
J Mol Cell Cardiol
; 54: 90-7, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23220127
13.
Hyperphosphorylation of mouse cardiac titin contributes to transverse aortic constriction-induced diastolic dysfunction.
Circ Res
; 109(8): 858-66, 2011 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-21835910
14.
Single-Molecule Force Spectroscopy on the N2A Element of Titin: Effects of Phosphorylation and CARP.
Front Physiol
; 11: 173, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32256378
15.
Protein changes contributing to right ventricular cardiomyocyte diastolic dysfunction in pulmonary arterial hypertension.
J Am Heart Assoc
; 3(3): e000716, 2014 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24895160