Detalhe da pesquisa
1.
Stimulation of soluble guanylate cyclase exerts antiinflammatory actions in the liver through a VASP/NF-κB/NLRP3 inflammasome circuit.
Proc Natl Acad Sci U S A
; 117(45): 28263-28274, 2020 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33106416
2.
sGC stimulator praliciguat suppresses stellate cell fibrotic transformation and inhibits fibrosis and inflammation in models of NASH.
Proc Natl Acad Sci U S A
; 116(22): 11057-11062, 2019 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31085647
3.
Soluble guanylate cyclase stimulator praliciguat attenuates inflammation, fibrosis, and end-organ damage in the Dahl model of cardiorenal failure.
Am J Physiol Renal Physiol
; 318(1): F148-F159, 2020 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31608671
4.
Pharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of Disease.
J Pharmacol Exp Ther
; 365(3): 664-675, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29643251
5.
Olinciguat, an Oral sGC Stimulator, Exhibits Diverse Pharmacology Across Preclinical Models of Cardiovascular, Metabolic, Renal, and Inflammatory Disease.
Front Pharmacol
; 11: 419, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32322204
6.
The soluble guanylate cyclase stimulator IW-1973 prevents inflammation and fibrosis in experimental non-alcoholic steatohepatitis.
Br J Pharmacol
; 175(6): 953-967, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29281143
7.
The Soluble Guanylate Cyclase Stimulator IWP-953 Increases Conventional Outflow Facility in Mouse Eyes.
Invest Ophthalmol Vis Sci
; 57(3): 1317-26, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26998718
8.
Discovery of IWP-051, a Novel Orally Bioavailable sGC Stimulator with Once-Daily Dosing Potential in Humans.
ACS Med Chem Lett
; 7(5): 465-9, 2016 May 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27190594
9.
Electrical and mechanical recovery of cardiac function following out-of-hospital cardiac arrest.
Resuscitation
; 84(1): 25-30, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22982154
10.
Minimizing pre- and post-defibrillation pauses increases the likelihood of return of spontaneous circulation (ROSC).
Resuscitation
; 81(7): 822-5, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20398991
11.
Clinical array comparative genomic hybridization: a new paradigm.
Expert Opin Med Diagn
; 2(4): 449-59, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23495710
12.
Klebsiella pneumoniae multiresistance plasmid pMET1: similarity with the Yersinia pestis plasmid pCRY and integrative conjugative elements.
PLoS One
; 3(3): e1800, 2008 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-18350140
13.
External guide sequences targeting the aac(6')-Ib mRNA induce inhibition of amikacin resistance.
Antimicrob Agents Chemother
; 51(6): 1918-25, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17387154
14.
Inhibition of aminoglycoside 6'-N-acetyltransferase type Ib-mediated amikacin resistance by antisense oligodeoxynucleotides.
Antimicrob Agents Chemother
; 47(10): 3296-304, 2003 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-14506044
15.
Complete nucleotide sequence of Klebsiella pneumoniae multiresistance plasmid pJHCMW1.
Antimicrob Agents Chemother
; 46(11): 3422-7, 2002 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-12384346