Detalhe da pesquisa
1.
The Chosen Few: Parallel Library Reaction Methodologies for Drug Discovery.
J Org Chem
; 87(4): 1880-1897, 2022 02 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34780177
2.
SAR of amino pyrrolidines as potent and novel protein-protein interaction inhibitors of the PRC2 complex through EED binding.
Bioorg Med Chem Lett
; 27(7): 1576-1583, 2017 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28254486
3.
SAR and characterization of non-substrate isoindoline urea inhibitors of nicotinamide phosphoribosyltransferase (NAMPT).
Bioorg Med Chem Lett
; 27(15): 3317-3325, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28610984
4.
ChemBeads-Enabled Photoredox High-Throughput Experimentation Platform to Improve C(sp2)-C(sp3) Decarboxylative Couplings.
ACS Med Chem Lett
; 14(4): 521-529, 2023 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37077401
5.
Design and Development of Glucocorticoid Receptor Modulators as Immunology Antibody-Drug Conjugate Payloads.
J Med Chem
; 65(6): 4500-4533, 2022 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35133822
6.
Development of Orally Efficacious Allosteric Inhibitors of TNFα via Fragment-Based Drug Design.
J Med Chem
; 64(1): 417-429, 2021 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33378180
7.
Biochemical and biophysical characterization of unique switch pocket inhibitors of p38α.
Bioorg Med Chem Lett
; 20(19): 5787-92, 2010 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20471255
8.
Structure-activity relationship studies on N'-aryl carbohydrazide P2X7 antagonists.
J Med Chem
; 51(10): 3030-4, 2008 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-18438986
9.
Correction to "Design and Development of Glucocorticoid Receptor Modulators as Immunology Antibody-Drug Conjugate Payloads".
J Med Chem
; 66(8): 6011, 2023 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37058612
10.
Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based Drug Design.
J Med Chem
; 61(24): 11074-11100, 2018 12 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30384606
11.
Discovery and pharmacological evaluation of growth hormone secretagogue receptor antagonists.
J Med Chem
; 49(15): 4459-69, 2006 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-16854051
12.
An Automated Microwave-Assisted Synthesis Purification System for Rapid Generation of Compound Libraries.
J Lab Autom
; 21(3): 459-69, 2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-26085482
13.
Discovery of A-971432, An Orally Bioavailable Selective Sphingosine-1-Phosphate Receptor 5 (S1P5) Agonist for the Potential Treatment of Neurodegenerative Disorders.
J Med Chem
; 58(23): 9154-70, 2015 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26509640
14.
Discovery of 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744) as a novel positive allosteric modulator of the alpha7 nicotinic acetylcholine receptor.
J Med Chem
; 52(10): 3377-84, 2009 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-19419141
15.
Discovery of a novel small molecule binding site of human survivin.
Bioorg Med Chem Lett
; 17(11): 3122-9, 2007 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17391963
16.
Scaffold oriented synthesis. Part 1: Design, preparation, and biological evaluation of thienopyrazoles as kinase inhibitors.
Bioorg Med Chem Lett
; 16(1): 96-9, 2006 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16216502
17.
Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels.
Bioorg Med Chem Lett
; 16(5): 1138-41, 2006 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16380257
18.
Isoindolinone ureas: a novel class of KDR kinase inhibitors.
Bioorg Med Chem Lett
; 14(17): 4505-9, 2004 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-15357981