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1.
Postgrad Med J ; 97(1151): 583-589, 2021 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32796117

RESUMO

BACKGROUND: The pattern and impact of burnout among the medical staff are not yet well defined. However, the consequences of burnout are not limited to the healthcare providers but also may affect their family, colleagues and patients in a negative manner. We aimed to assess the characteristics and predictors of burnout among health professionals at two large tertiary hospitals. METHODS: We conducted a cross-sectional study during the period from July 2018 to 31 December 2018. Data, via Maslach Burnout Inventory survey, were collected from physicians and other healthcare workers in two hospitals. RESULTS: A total of 624 responses to questionnaires were analysed. Half of the respondents were physicians, and men constituted the majority. About 10% (95% CI, 7.8 to 12.5) of the respondents satisfied the criteria of burnout. Emotional exhaustion (EE) was observed in 45.7%, depersonalisation (DP) in 26.9% and personal accomplishment (PA) in 41.2% of the respondents. There was a positive correlation between EE and DP (r=0.627, p=0.001), and a weak negative correlation between DP and PA (r=-0.195, p=0.001). Young age, less experience, trauma surgery, lack of habits and getting depressed ≥1 time/week were predictors of burnout. CONCLUSIONS: Burnout affects one-tenth of the health professionals in the tertiary hospitals in Qatar. Physicians are more likely to have higher DP and lower PA, whereas nurses prone to have higher EE. In this study, no gender discrepancy is appreciated and the junior medical staff is at a higher risk of burnout.


Assuntos
Esgotamento Profissional/psicologia , Esgotamento Psicológico , Pessoal de Saúde/psicologia , Adulto , Estudos Transversais , Atenção à Saúde , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Satisfação Pessoal , Estudos Prospectivos , Catar , Centros de Atenção Terciária
2.
Aging Male ; 23(5): 1066-1072, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31608745

RESUMO

OBJECTIVE: Preventing pressure ulcers is an essential part of patient care and it is important to be aware of the best way to prevent it. Hence, the present study aims to look for the demographics, clinical characteristics, and risk factors in patients with and without pressure ulcer among elderly patients. METHODS: A retrospective longitudinal study was conducted in elderly (above 65 years) patients from a period of October 2014 to October 2015 in the medical ward under acute Geriatric care at Hamad General Hospital in Qatar. RESULTS: Overall, a total of 90 patients were included with an average age of 79 ± SD 11.3 years of which 45 patients developed pressure ulcer. There was male (64.4%) preponderance in the study population. Most common comorbidity was hypertension (77.8%). Anemia correction (91%), high protein diet supplementation (1.5 g/kg body wt.) (100%), and 2 h repositioning (100%) were implemented for majority of the pressure ulcer patients as preventive intervention. CONCLUSIONS: From the study finding, it is observed that, anemia correction, high protein diet supplementation and 2 h repositioning are the best practices for the management of pressure ulcer. Hence, these best practices are recommended for the early prevention of pressure ulcer among elderly.


Assuntos
Úlcera por Pressão , Idoso , Humanos , Estudos Longitudinais , Masculino , Úlcera por Pressão/epidemiologia , Úlcera por Pressão/prevenção & controle , Catar/epidemiologia , Estudos Retrospectivos , Centros de Atenção Terciária
3.
Am J Emerg Med ; 38(2): 266-271, 2020 02.
Artigo em Inglês | MEDLINE | ID: mdl-31060862

RESUMO

PURPOSE: The purpose of this study was to test the efficacy of prehospital administration of tranexamic acid (TXA) to injured patients on mortality, thromboembolic events and need for blood transfusion in a level 1 trauma center. METHODS: We conducted a retrospective study comparing adult trauma patients receiving or not receiving prehospital TXA between January 2017 and September 2018. Patients not receiving TXA but transfused within 4 h of admission were 1:1 matched to TXA-treated patients for age, sex, injury severity score, head abbreviated injury score, prehospital heart rate and systolic blood pressure. RESULTS: In total 204 patients were included (102 TXA and 102 control), with a mean age of 31 years. On admission, shock index (p = 0.03) and serum lactate (p = 0.001) were greater in the control group, whereas the initial base deficit, hemoglobin levels and EMS time were comparable in both groups. The odd ratio (OR) for shock index ≥0.9 after TXA administration was 0.44 (95% CI 0.23-0.84). The median amount of blood transfusion was greater in the control group [eight units (range 1-40) vs three (range 0-40), p = 0.01] as well as the use of massive blood transfusion [OR 0.35 (95% CI 0.19-0.67)]. In the TXA group, VTE was higher [OR 2.0 (95% CI 0.37-11.40)]; whereas the overall mortality was lower [OR 0.78 (95% CI 0.42-1.45)] without reaching statistical significance. CONCLUSIONS: Prehospital TXA administration is associated with less in-hospital blood transfusion and massive transfusion protocol (MTP). There is no significant increase in the thromboembolic events and mortality, however, further evaluation in larger clinical trials is needed.


Assuntos
Serviços Médicos de Emergência/normas , Ácido Tranexâmico/administração & dosagem , Ferimentos e Lesões/tratamento farmacológico , Administração Intravenosa/métodos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Serviços Médicos de Emergência/métodos , Serviços Médicos de Emergência/estatística & dados numéricos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Catar/epidemiologia , Estudos Retrospectivos , Análise de Sobrevida , Ácido Tranexâmico/uso terapêutico , Centros de Traumatologia/organização & administração , Centros de Traumatologia/estatística & dados numéricos , Ferimentos e Lesões/epidemiologia , Ferimentos e Lesões/mortalidade
4.
J Relig Health ; 59(4): 1810-1823, 2020 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31309441

RESUMO

Medical advancements over the past decades brought organ transplantation as a definitive therapy for different end-stage organ failure. However, non-availability of organs required for transplantation is a major challenge worldwide. We aimed to determine the knowledge and willingness to donate organs in various populations and settings in the Middle Eastern region. Literature searches were conducted on PubMed, MEDLINE, Cochrane, and Google scholar electronic databases. Different combinations of search terms such as "organ donation"; "knowledge", "awareness"; "beliefs", "willingness"; and "attitude" along with the country names were used. Additional searches using reference lists of studies and review articles were conducted. Data were extracted using standardized excel form and pilot tested. Three authors independently abstracted the data using a data collection form. Results from different studies were pooled for the analysis when appropriate. The search yielded 1806 articles; 1000 duplicates and review articles were excluded, and a further 792 articles not relevant were excluded. Finally, 14 original studies met the inclusion criteria. Total pooled sample size for assessing knowledge was 6697 and for willingness was 8714. Pooled overall knowledge regarding organ donation was 69% with a 95% CI [64.5, 73.5]. Pooled overall willingness to donate organ was 49.8% with a 95% CI [41.3, 58.4]. Knowledge about organ donation and willingness to donate organs varies in different population and settings in the Middle East. These in fact are linked to multiple social factors ultimately leads to 'consent' for donating organs by a potential donor. Family's influence; religious, traditional and spiritual beliefs; and status of ethnic, minority, and immigrant populace are the important determinants of the decision for organ donation. Understandings on social determinants in organ donation remain crucial and should be addressed while developing policies and organizational developments.


Assuntos
Conhecimentos, Atitudes e Prática em Saúde , Doadores de Tecidos , Humanos , Oriente Médio , Transplante de Órgãos/psicologia , Inquéritos e Questionários , Doadores de Tecidos/psicologia , Doadores de Tecidos/estatística & dados numéricos , Obtenção de Tecidos e Órgãos/estatística & dados numéricos
5.
Am J Emerg Med ; 37(1): 133-142, 2019 01.
Artigo em Inglês | MEDLINE | ID: mdl-30318278

RESUMO

OBJECTIVE: The association between brain injury and elevated serum cardiac troponin (cTn) remains poorly understood. We conducted a systematic review and meta-analysis to evaluate whether elevated cTn increases the risk of mortality in patients with traumatic (TBI) or non-traumatic brain injury (NT-BI). METHODS: Cochrane Library, MEDLINE, PubMed, Scopus, Cochrane Central Register of Controlled Trials (CENTRAL), WHO International Clinical Trials Registry Platform, and Google scholar databases, and clinicaltrials.gov were searched for a retrospective, prospective and randomized clinical trials (RCT) or quasi-RCT studies that assessed the effect of elevated cTn (conventional or high sensitive assay) on the outcomes of brain injury patients. The main outcome of interest was mortality. Two authors independently abstracted the data using a data collection form. Results from different studies were pooled for analysis, whenever appropriate. The total number of patients pooled was 2435, of which 916 had elevated cTn and 1519 were in control group. RESULTS: Out of 691 references identified through the search, 8 analytical studies met inclusion criteria. Among both types of brain injuries, an elevated cTn was associated with a higher mortality with an overall pooled odd ratio (OR) of 3.37 (95% CI 2.13-5.36). The pooled OR for mortality was 3.31 (95% CI 1.99-5.53) among patients with TBI and 3.36 (95% CI 1.32-8.6) among patients with NT-BI. CONCLUSIONS: Pooled analysis indicates that elevated cTn is significantly associated with a high mortality in patients with TBI and NT-BI. Prospective clinical trials are needed to support these findings and to inform a biomarker risk stratification regardless of the mechanism of injury.


Assuntos
Lesões Encefálicas Traumáticas/sangue , Lesões Encefálicas Traumáticas/mortalidade , Lesões Encefálicas/sangue , Lesões Encefálicas/mortalidade , Troponina C/sangue , Biomarcadores/sangue , Lesões Encefálicas/diagnóstico , Lesões Encefálicas Traumáticas/diagnóstico , Humanos , Prognóstico
6.
Am J Emerg Med ; 36(6): 1079-1087, 2018 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-29573898

RESUMO

OBJECTIVE: Antifibrinolytic agent tranexamic acid (TXA) has a potential clinical benefit for in-hospital patients with severe bleeding but its effectiveness in pre-hospital settings remains unclear. We conducted a systematic review and meta-analysis to evaluate whether pre-hospital administration of TXA compared to placebo improve patients' outcomes? METHODS: PubMed, MEDLINE, Cochrane Library, WHO International Clinical Trials Registry Platform, Cochrane Central Register of Controlled Trials (CENTRAL), Scopus, clinicaltrials.gov and Google scholar databases were searched for a retrospective, prospective and randomized (RCT) or quasi-RCT studies that assessed the effect of prehospital administration of TXA versus placebo on the outcomes of trauma patients with significant hemorrhage. The main outcomes of interest were 24hour 30-day mortality and in-hospital thromboembolic complications. Two authors independently abstracted the data using a data collection form. Results from different studies were pooled for the analysis, when appropriate. RESULTS: Out of 92 references identified through the search, two analytical studies met the inclusion criteria. The effect of TXA on 24-hour mortality had a pooled odds ratio (OR) of 0.49 (95% CI 0.28-0.85), 30-day mortality OR of 0.86 (95% CI, 0.56-1.32), and thromboembolic events OR of 0.74 (95% CI, 0.27-2.07). CONCLUSION: Prehospital TXA appears to reduce early mortality in trauma patients. The pooled analysis also shows a trend toward lower 30-day mortality and reduced risk of thromboembolic events. Additional randomized controlled clinical trials are needed to determine the significance of these trends.


Assuntos
Serviços Médicos de Emergência/métodos , Hemorragia/prevenção & controle , Ensaios Clínicos Controlados Aleatórios como Assunto/métodos , Ácido Tranexâmico/administração & dosagem , Ferimentos e Lesões/complicações , Antifibrinolíticos/administração & dosagem , Relação Dose-Resposta a Droga , Hemorragia/etiologia , Humanos , Resultado do Tratamento , Ferimentos e Lesões/tratamento farmacológico
7.
BMC Microbiol ; 17(1): 113, 2017 05 15.
Artigo em Inglês | MEDLINE | ID: mdl-28506251

RESUMO

BACKGROUND: Poultry farming and consumption of poultry (Gallus gallus domesticus) meat and eggs are common gastronomical practices worldwide. Till now, a detailed understanding about the gut colonisation of Gallus gallus domesticus by yeasts and their virulence properties and drug resistance patterns in available literature remain sparse. This study was undertaken to explore this prevalent issue. RESULTS: A total of 103 specimens of fresh droppings of broiler chickens (commercial G domesticus) and domesticated chickens (domesticated G domesticus) were collected from the breeding sites. The isolates comprised of 29 (33%) Debaryozyma hansenii (Candida famata), 12 (13.6%) Sporothrix catenata (C. ciferrii), 10 (11.4%) C. albicans, 8 (9.1%) Diutnia catenulata (C. catenulate), 6 (6.8%) C. tropicalis, 3 (3.4%) Candida acidothermophilum (C. krusei), 2 (2.3%) C. pintolopesii, 1 (1.1%) C. parapsilosis, 9 (10.2%) Trichosporon spp. (T. moniliiforme, T. asahii), 4 (4.5%) Geotrichum candidum, 3 (3.4%) Cryptococcus macerans and 1 (1%) Cystobasidium minuta (Rhodotorula minuta). Virulence factors, measured among different yeast species, showed wide variability. Biofilm cells exhibited higher Minimum Inhibitory Concentration (MIC) values (µg/ml) than planktonic cells against all antifungal compounds tested: (fluconazole, 8-512 vs 0.031-16; amphotericin B, 0.5-64 vs 0.031-16; voriconazole 0.062-16 vs 0.062-8; caspofungin, 0.062-4 vs 0.031-1). CONCLUSIONS: The present work extends the current understanding of in vitro virulence factors and antifungal susceptibility pattern of gastrointestinal yeast flora of G domesticus. More studies with advanced techniques are needed to quantify the risk of spread of these potential pathogens to environment and human.


Assuntos
Antifúngicos/farmacologia , Biodiversidade , Microbioma Gastrointestinal/efeitos dos fármacos , Fatores de Virulência , Virulência , Leveduras/classificação , Leveduras/efeitos dos fármacos , Anfotericina B/farmacologia , Animais , Biofilmes/efeitos dos fármacos , Biofilmes/crescimento & desenvolvimento , Caspofungina , Galinhas/microbiologia , Contagem de Colônia Microbiana/veterinária , Farmacorresistência Fúngica/efeitos dos fármacos , Equinocandinas/farmacologia , Fluconazol/farmacologia , Lipopeptídeos/farmacologia , Testes de Sensibilidade Microbiana/veterinária , Nepal , Aves Domésticas/microbiologia , Voriconazol/farmacologia , Leveduras/isolamento & purificação
9.
BMC Psychiatry ; 13: 96, 2013 Mar 22.
Artigo em Inglês | MEDLINE | ID: mdl-23522357

RESUMO

BACKGROUND: Currently a large number of atypical antipsychotics available in the market are endorsed as better option for treating schizophrenia than the typical antipsychotics. Information regarding the utilization pattern of antipsychotic drugs is lacking in Nepalese population particularly in Western Nepal. By means of this study one is expected to acquire an idea concerning clinician's preference to the antipsychotic drugs in actual clinical setup. The main objective of the study was to find the commonest antipsychotics prescribed in a tertiary care center among hospitalized patients in Western Nepal. METHODS: This cross sectional study was carried out between 1st January 2009 and 31th December 2010 at Manipal Teaching Hospital, Nepal. The diagnosis of schizophrenia was based on ICD-10 (Tenth revision).The main outcome variables of the study was commonest antipsychotic drug prescribed. Z test, Chi square test and logistic regression were used for analytical purpose. P-value < 0.05 was considered to be statistically significant. This is the first study done on the utilization pattern of antipsychotics drugs among hospitalized patients in Nepal. RESULTS: Out of 210 cases of schizophrenia, most of the patients were less than 40 yrs. 78.6%, male 61.9%, unemployed 86.7% and having their monthly income less than NPR 10000 /month 80.5%. As far as religion, 78.1% patients were the Hindus and ethnically schizophrenia was common among the Dalit 26.2%. The study revealed that 46.2% of patients were students followed by 25.2% of housewives. Olanzapine was the commonest antipsychotic drug to be prescribed 34.3%. It was observed that the psychiatrists had a tendency of using antipsychotic drugs by trade names [OR 3.3 (1.407, 8.031)] in male patients as compared to female patients. CONCLUSION: According to the utilization pattern of antipsychotics, it is concluded that atypical antipsychotics were used relatively more commonly than that of typical antipsychotics. Among the atypical antipsychotic drugs, there is a trend of using Olanzapine during Schizophrenia as compared to other atypical antipsychotic drugs in Western Nepal.


Assuntos
Antipsicóticos/uso terapêutico , Benzodiazepinas/uso terapêutico , Uso de Medicamentos/estatística & dados numéricos , Pacientes Internados/estatística & dados numéricos , Esquizofrenia/tratamento farmacológico , Adulto , Fatores Etários , Estudos Transversais , Prescrições de Medicamentos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Nepal , Olanzapina , Esquizofrenia/epidemiologia , Fatores Sexuais , Fatores Socioeconômicos
10.
BMC Pediatr ; 13: 43, 2013 Mar 27.
Artigo em Inglês | MEDLINE | ID: mdl-23536998

RESUMO

BACKGROUND: Seizure is one of the common causes of childhood hospitalization with significant mortality and morbidity. There is limited data regarding acute seizures episodes form the developing countries. Current study aims to find the common etiology of seizure and classify seizure types in various age groups presenting to tertiary center in Western Nepal. METHODS: This was a hospital based retrospective study carried out in the data retrieved from the records maintained in the Department of Pediatrics, Manipal Teaching Hospital, Pokhara from 1st July 2007 to 31st July 2011.Variables collected were demographics, clinical presentations, laboratory tests, brain imaging studies, electroencephalography, diagnosis and hospital course. RESULTS: A total of 551 patients were admitted for seizures with 338 (61.3%) males and 213 (38.7%) females. Among these patients, 295 (53.5%) presented with fever and 317 (57.5%) of children were less than 5 years of age. Generalized tonic-clonic seizures were the most common seizure type (69.9%). Seizure disorder (33.4%), febrile seizures (30.7%), CNS infections and neurocysticercosis were common etiologies. Abnormal brain images were noted in 111 (45.9%) of 242 patients and most common abnormality was neurocysticercosis 66 (59.5%). CONCLUSION: CNS infections and febrile convulsions were common causes of seizures in febrile children. Neuroimaging should be advised in all afebrile children for the diagnosis of neurocysticercosis. Children diagnosed as seizure disorder require long term follow up studies including neurophysiologic studies.


Assuntos
Países em Desenvolvimento , Hospitalização , Convulsões , Doença Aguda , Adolescente , Infecções do Sistema Nervoso Central/complicações , Infecções do Sistema Nervoso Central/diagnóstico , Infecções do Sistema Nervoso Central/epidemiologia , Infecções do Sistema Nervoso Central/terapia , Criança , Pré-Escolar , Eletroencefalografia , Epilepsia/diagnóstico , Epilepsia/epidemiologia , Epilepsia/terapia , Feminino , Humanos , Lactente , Imageamento por Ressonância Magnética , Masculino , Nepal , Neurocisticercose/complicações , Neurocisticercose/diagnóstico , Neurocisticercose/epidemiologia , Neurocisticercose/terapia , Prevalência , Estudos Retrospectivos , Convulsões/diagnóstico , Convulsões/etiologia , Convulsões/terapia , Convulsões Febris/diagnóstico , Convulsões Febris/epidemiologia , Convulsões Febris/terapia , Centros de Atenção Terciária , Tomografia Computadorizada por Raios X , Resultado do Tratamento
11.
Nepal J Epidemiol ; 13(4): 1294-1297, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-38299042

RESUMO

Nanoparticles (NPs) are small particles with a surface area ranging from 1 to 100 nm in diameter that are rampantly used in different fields, e.g., medicine, engineering, and others. Because of their unique properties, such as their tiny size, magnetic properties, quantum size effects, and macroscopic quantum tunnelling effects, they are crucial for a wide range of potential applications. NPs play a significant role in the treatment of vascular disorders, the production of vaccines, and the development of drug carriers for diverse therapies due to their bioavailability, targeting ability, and efficacy. However, significant risks to the environment and health are also associated with it. NPs cause necrotic plasma membrane rupture or apoptosis, which leads to cell death. NPs interfere with cell signalling, endosomal membranes, and organelles like the nucleus or mitochondria, affecting their function. NPs cause autophagic cell death, which causes a stress response and sterile inflammation. The primary routes for the entry of NPs into the human body are inhalation, ingestion, and skin contact. NPs accumulate in the respiratory system based on their size, shape, and surface properties. NPs can cause lung inflammation and fibrosis, disrupt the endocrine system by attaching to hormone receptors, and produce reactive oxygen species (ROS) associated with DNA damage, oligospermia, and male infertility. Carcinogenic properties of NPs cause mutations, apoptosis, and inflammatory responses. Collaborative research between ecologists and epidemiologists may enlighten ways to reduce the harmful effects of NPs.

12.
Nepal J Epidemiol ; 13(3): 1288-1291, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-38293634

RESUMO

Systematic reviews that are out-of-date delay policymaking, create controversy, and can erode trust in research. To avoid this issue, it is preferable to keep summaries of the study evidence. Living evidence is a synthesis approach that provides up-to-date rigorous research evidence summaries to decision-makers. This strategy is particularly useful in rapidly expanding research domains, uncertain existing evidence, and new research that may impact policy or practice, ensuring that physicians have access to the most recent evidence. Addressing global challenges - ranging from public health crises to climate change or political instability - requires evidence-based judgements. An obsolete, biased, or selective information poses risks of poor decisions and resource misallocation. The relatively nascent practice of living evidence proves invaluable in maintaining continuous interest and team engagement. The concept of living evidence has been particularly relevant during the COVID-19 pandemic due to the rapidly evolving nature of the virus, the urgent need for timely information, and the continuous emergence of new research findings. Although the COVID-19 pandemic accelerated the adoption of evidence systems, researchers and funders of research should rigorously test the living-evidence model across diverse domains to further advance and optimize its methodology.

13.
Front Psychiatry ; 14: 1279663, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-38260774

RESUMO

Purpose: This study aimed to examine the impact of the COVID-19 pandemic on the lifestyle behaviors which included physical activity, sedentariness, healthy eating habits, sleep habits, and tobacco use in persons with and without disabilities in Qatar. Methods: This cross-sectional study used a structured, online questionnaire. The collected data included demographics, mental health, physical health, eating habits, body weight, sleep, and nicotine intake. This study was conducted between September 25, 2020, and December 31, 2020. Results: Seventy respondents from Qatar participated in the study. Pre-pandemic healthy lifestyle behaviors (physical activity, healthy diet, sleep, etc.) showed no significant differences between people with and without disabilities. However, perceived changes in mental and physical health and eating habits during the pandemic lockdown differed between people with and without disabilities. People with disabilities reported worsening mental health (64.7%), physical health (53%), and dietary habits compared to the pre-pandemic levels. Furthermore, the more severe the disability, the more significant is its impact on mental and physical health. Conclusion: This study indicated that the pandemic has had a significant impact on the mental and physical health of people with and without disabilities in Qatar. These findings reveal how closely individuals with disabilities and their lifestyle choices are related to their mental and physical well-being. This will enable the development of specific interventions for similar situations in the future.

14.
Nepal J Epidemiol ; 13(2): 1268-1284, 2023 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-37692909

RESUMO

Indian subcontinent has high mental heath burden and low resources to cope the mental health challenges. Assessment of impact of COVID-19 pandemic on the mental health would help to prioritize the resource allocations. We aimed to assess the impact of COVID-19 on the mental health of people in the Indian subcontinent. Following the PRISMA 2020 guideline, a scoping review was performed by systematically searching the PubMed, Scopus, and Embase databases to identify original studies that assessed mental health conditions during the COVID-19 pandemic in the Indian subcontinent. In this review, a total of 34 studies conducted between 2020 and 2022 were analyzed. The prevalence of anxiety disorders was found to range widely, from 2.5% in North Indian urban slum to 53% in Bangladesh and 21.7% in Pakistan. Similarly, the prevalence of depression varied widely, with rates ranging from 3.5% in North India to 29.8% in Pakistan. The prevalence of stress-related problems ranged from 18.3% in Pakistan to 59.7% in Bangladesh. Factors such as female gender, married status, healthcare workers, and mental illness were identified as important predictors of anxiety and depressive disorders. The impact of COVID-19 pandemic on mental health in Indian subcontinent varies widely based on study population and methods. Therefore, a cautious interpretation is needed while generalizing the study results.

15.
Nepal J Epidemiol ; 12(2): 1215-1219, 2022 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-35974973

RESUMO

The global pandemic caused by the SARS-CoV-2 virus has affected every continent worldwide. The novelty of this virus, its mutations and the rapid speed and unprecedented rate at which it has torn through the global community has in turn lead to an innate lack of knowledge and information about the actual disease caused and the severity of the complications associated with COVID-19. The SARS-CoV-2 virus has been infecting individuals since 2019 and now as of 2022 has been circulating for just over 2 years within the global populous. As the number of cases have risen globally over this period (some of which having contracted the virus twice) further endeavours have been undertaken to better understand the pathogenesis and natural progression of the disease. A condition reported in some cases with extended bouts of sickness or symptoms following the initial infection with COVID was labelled "long COVID" towards the earlier phases of the pandemic (in the spring of 2020), but has only recently gained the global media and medical attention due to its affliction of more individuals on a global basis and has thus warranted further investigation. Long COVID is described as a persistent, long-term state of poor health following an infection with COVID-19. The effect of Long COVID is multisystemic in nature with a wide array of signs and symptoms. The most commonly reported clinical features of long COVID are: headaches, myalgia, chest pain, rashes, abdominal pain, shortness of breath, palpitations, anosmia, persistent cough, brain fogs, forgetfulness, depression, insomnia, fatigue and anxiety. This research aims to explore the symptomatology, pathophysiology as well as the treatment and prevention of Long COVID.

16.
Nepal J Epidemiol ; 12(1): 1175-1178, 2022 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-35528457

RESUMO

This paper illustrates the growing importance of mixed-methods research to many health disciplines ranging from nursing to epidemiology. Mixed-methods approaches requires not only the skills of the individual quantitative and qualitative methods but also a skill set to bring two methods/datasets/findings together in the most appropriate way. Health researchers need to pay careful attention to the 'best' approach to designing, implementing, analysing, integrating both quantitative (number) and qualitative (word) information and writing this up in a way offers greater insights and enhances its applicability. This paper highlights the strengths and weaknesses of mixed-methods approaches as well as some of the common mistakes made by researchers applying mixed-methods for the first time.

17.
Nepal J Epidemiol ; 12(3): 1224-1230, 2022 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-36407053

RESUMO

Background: Panic buying has been reported during a period of crisis when people buy an extra amount of essential commodities and hoard them anticipating their future utility. As a newer entity, a bibliometric analysis would reveal the research gaps for further studies. We aimed to do a bibliometric analysis of researches published on panic buying over the past two decades. Methods: A literature search was conducted in the SCOPUS database using the keyword "panic buying". All published research in the English language between 1st January 2001 to 1st August 2021 was included in the analysis of this study. Results: We identified a total of 142 articles on panic buying published over the past two decades. There is an exponential increase in the publication on this topic during the COVID-19 pandemic (n=127). Majority of the articles were published from the United States (n=23), followed by the United Kingdom (n=20), and China (n=20). The Frontiers in Public Health and Journal of Retailing and Consumer Services published the highest number of articles (eight each). Arafat SMY published the highest number of publications as a single author (n=10) and Enam Medical College and Hospital, Bangladesh has the highest number of papers as an institution (n=10). Among all the publishers, Elsevier has published the maximum number of papers (n=38). Conclusion: There is an exponential growth of panic buying research during 2020-21. The global crisis of the COVID-19 pandemic has been attributed to the recent rise in panic buying research.

18.
Nepal J Epidemiol ; 12(2): 1203-1214, 2022 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-35974971

RESUMO

Background: Globally, post traumatic stress disorder (PTSD) is one of the most common psychiatric illnesses following a disaster. We aimed to evaluate the relationship between the socio-economic and flood exposure factors with PTSD, depression and anxiety among the flood-affected populations in Kerala, India. Methods: A cross-sectional household survey was conducted from November 2019 to January 2020 in Kozhikode district of Kerala, India. Adults (≥ 18 years), who were permanent residents and had been directly exposed to the flood, were invited to take part in the study. Individuals with a history of mental health issues and those who had other stressful situations in the past were excluded. The survey questionnaire was based on three screening tools: (1) PTSD Checklist for DSM-5 (PCL-5); (2) patient health questionnaire (PHQ-9); and (3) generalized anxiety disorder (GAD-7). Data included sociodemographic factors and flood exposure variables. The primary outcome variable was psychiatric morbidity (PTSD, anxiety and depression). Results: A total of 276 respondents (150 males/126 females) participated in the study. A significant correlation was observed between total score on PCL-5 and GAD-7 (r=0.339, p=0.001) and PHQ-9 (r=0.262, p=0.001). Females had significantly higher total PTSD symptom severity scores (8.24±5.88 vs. 6.07±5.22; p=0.001), severity of symptoms of intrusion (4.66±3.60 vs. 3.69±3.20; p=0.04), increased level of anxiety (2.54±1.94 vs. 1.79±1.53; p=0.001) and depression (3.02±2.26 vs. 2.04±1.67; p=0.001) compared to males. However, the gender difference for PTSD symptoms disappeared when controlling for age. Conclusion: The findings of this survey revealed that the vast majority of respondents (92 percent females and 87 percent males) still had subclinical psychiatric symptoms one year after the flood. Therefore, tailored psychological interventions are warranted to counter the long-lasting impact of flooding on the mental health of individuals.

19.
Artigo em Inglês | MEDLINE | ID: mdl-35162635

RESUMO

Work-related injuries (WRIs) are recognized as a leading cause of admission to the national trauma center of Qatar. A retrospective analysis of trauma registry data and electronic medical records was conducted on a cohort of all WRI patients who were admitted to the Hamad Trauma Center (HTC), in Doha, Qatar, between 2011 and 2017. A total of 3757 WRI patients were treated at the HTC over the 7-year study period. The overall cost for treatment was 124,671,431 USD (18 million USD per year), with a median cost of 19,071 USD. There was a strong positive correlation between the overall cost and hospital-stay cost (r2 = 0.949, p = 0.00001) and between the overall cost and procedure cost (r2 = 0.852, p = 0.00001). Motor vehicle crash (MVC) victims who wore seatbelts had significantly lower injury severity, hospital stay and median total costs. A comparison of patients by quartiles of the costs incurred showed that the proportions of MVC victims, pedestrian injuries and mortality were significantly higher in the fourth quartile when compared to other quartiles (p < 0.05). These findings suggest that investments in the primary prevention of work-related injuries from falls and MVCs, through proven interventions, should be priorities for occupational safety and health in Qatar.


Assuntos
Traumatismos Ocupacionais , Ferimentos e Lesões , Acidentes de Trânsito , Custos de Cuidados de Saúde , Humanos , Escala de Gravidade do Ferimento , Catar/epidemiologia , Estudos Retrospectivos , Centros de Traumatologia , Ferimentos e Lesões/epidemiologia
20.
Nepal J Epidemiol ; 12(4): 1242-1247, 2022 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-36741769

RESUMO

Knife crime has become a common phrase used by the media, but it is not always clear what it refers to or what they mean when they use the term. Knife crime can cover many offences, making it challenging to define and estimate its prevalence. This review aimed to evaluate potential knife crimes in the UK from 2011 to 2021 and analyse the causes and risk factors associated with the crimes. Six UK online news portals were purposefully chosen to be included in the study, and knife crime news was searched retrospectively. The term "knife crime" was used to search. The news portals were the: Metro, the Sun, the Guardian, Daily Mail, Daily Mirror and the Evening Standard. In the assigned news portals, 692 reports were found between January 2011 and December 2021. The study revealed that the 11-20 years of age group individuals are more vulnerable as victims, and males are more reported as victims when compared to females. About 61.8% of knife crimes are reported from South England. Knife crime risk is higher in early adulthood and among males. Street violence, fights/gang attacks, family issues and robbery are the leading causes of knife crime and have all been identified as risk factors that must be addressed with caution.

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