Detalhe da pesquisa
1.
Dose optimization of an adjuvanted peptide-based personalized neoantigen melanoma vaccine.
PLoS Comput Biol
; 20(3): e1011247, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38427689
2.
Endotoxin contamination in commercially available Cas9 proteins potentially induces T-cell mediated responses.
Gene Ther
; 30(7-8): 575-580, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34744169
3.
Mathematical model of a personalized neoantigen cancer vaccine and the human immune system.
PLoS Comput Biol
; 17(9): e1009318, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34559809
4.
Clinical manifestation of hemophilia A in the absence of mutations in the F8 gene that encodes FVIII: role of microRNAs.
Transfusion
; 60(2): 401-413, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31785023
5.
A Foundational Study for Normal F8-Containing Mouse Models for the miRNA Regulation of Hemophilia A: Identification and Analysis of Mouse miRNAs that Downregulate the Murine F8 Gene.
Int J Mol Sci
; 21(16)2020 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32781510
6.
Role of microRNAs in Hemophilia and Thrombosis in Humans.
Int J Mol Sci
; 21(10)2020 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32443696
7.
Translational and transcriptional responses in human primary hepatocytes under hypoxia.
Am J Physiol Gastrointest Liver Physiol
; 316(6): G720-G734, 2019 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30920299
8.
Single synonymous mutation in factor IX alters protein properties and underlies haemophilia B.
J Med Genet
; 54(5): 338-345, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28007939
9.
Exposing synonymous mutations.
Trends Genet
; 30(7): 308-21, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24954581
10.
The intron-22-inverted F8 locus permits factor VIII synthesis: explanation for low inhibitor risk and a role for pharmacogenomics.
Blood
; 125(2): 223-8, 2015 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25406352
11.
Understanding the contribution of synonymous mutations to human disease.
Nat Rev Genet
; 12(10): 683-91, 2011 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-21878961
12.
Large scale analysis of the mutational landscape in HT-SELEX improves aptamer discovery.
Nucleic Acids Res
; 43(12): 5699-707, 2015 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25870409
13.
Polymorphisms in the F8 gene and MHC-II variants as risk factors for the development of inhibitory anti-factor VIII antibodies during the treatment of hemophilia a: a computational assessment.
PLoS Comput Biol
; 9(5): e1003066, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23696725
14.
Application of machine learning approaches for predicting hemophilia A severity.
J Thromb Haemost
; 2024 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38718927
15.
Factor VIII moiety of recombinant Factor VIII Fc fusion protein impacts Fc effector function and CD16+ NK cell activation.
Front Immunol
; 15: 1341013, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38655263
16.
Investigation of thrombin concentration at the time of clot formation in simultaneous thrombin and fibrin generation assays.
Sci Rep
; 14(1): 9225, 2024 04 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38649717
17.
Engineering and evaluation of FXa bypassing agents that restore hemostasis following Apixaban associated bleeding.
Nat Commun
; 15(1): 3912, 2024 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38724509
18.
Proceedings of the 14th European immunogenicity platform open symposium on immunogenicity of biopharmaceuticals.
MAbs
; 16(1): 2324801, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38441119
19.
Cyclosporin A impairs the secretion and activity of ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 repeat).
J Biol Chem
; 287(53): 44361-71, 2012 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23144461
20.
Identification of sequence-structure RNA binding motifs for SELEX-derived aptamers.
Bioinformatics
; 28(12): i215-23, 2012 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22689764