Pesquisa | Biblioteca Virtual em Saúde

1.

B lymphocyte-derived acetylcholine limits steady-state and emergency hematopoiesis.

Schloss, Maximilian J; Hulsmans, Maarten; Rohde, David; Lee, I-Hsiu; Severe, Nicolas; Foy, Brody H; Pulous, Fadi E; Zhang, Shuang; Kokkaliaris, Konstantinos D; Frodermann, Vanessa; Courties, Gabriel; Yang, Chongbo; Iwamoto, Yoshiko; Knudsen, Anders Steen; McAlpine, Cameron S; Yamazoe, Masahiro; Schmidt, Stephen P; Wojtkiewicz, Gregory R; Masson, Gustavo Santos; Gustafsson, Karin; Capen, Diane; Brown, Dennis; Higgins, John M; Scadden, David T; Libby, Peter; Swirski, Filip K; Naxerova, Kamila; Nahrendorf, Matthias.

Nat Immunol ; 23(4): 605-618, 2022 04.

Artigo em Inglês | MEDLINE | ID: mdl-35352063

2.

A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia.

Baryawno, Ninib; Przybylski, Dariusz; Kowalczyk, Monika S; Kfoury, Youmna; Severe, Nicolas; Gustafsson, Karin; Kokkaliaris, Konstantinos D; Mercier, Francois; Tabaka, Marcin; Hofree, Matan; Dionne, Danielle; Papazian, Ani; Lee, Dongjun; Ashenberg, Orr; Subramanian, Ayshwarya; Vaishnav, Eeshit Dhaval; Rozenblatt-Rosen, Orit; Regev, Aviv; Scadden, David T.

Cell ; 177(7): 1915-1932.e16, 2019 06 13.

Artigo em Inglês | MEDLINE | ID: mdl-31130381

3.

Rapid Mobilization Reveals a Highly Engraftable Hematopoietic Stem Cell.

Hoggatt, Jonathan; Singh, Pratibha; Tate, Tiffany A; Chou, Bin-Kuan; Datari, Shruti R; Fukuda, Seiji; Liu, Liqiong; Kharchenko, Peter V; Schajnovitz, Amir; Baryawno, Ninib; Mercier, Francois E; Boyer, Joseph; Gardner, Jason; Morrow, Dwight M; Scadden, David T; Pelus, Louis M.

Cell ; 172(1-2): 191-204.e10, 2018 01 11.

Artigo em Inglês | MEDLINE | ID: mdl-29224778

4.

Angiogenin Promotes Hematopoietic Regeneration by Dichotomously Regulating Quiescence of Stem and Progenitor Cells.

Goncalves, Kevin A; Silberstein, Lev; Li, Shuping; Severe, Nicolas; Hu, Miaofen G; Yang, Hailing; Scadden, David T; Hu, Guo-Fu.

Cell ; 166(4): 894-906, 2016 Aug 11.

Artigo em Inglês | MEDLINE | ID: mdl-27518564

5.

Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells.

Yu, Vionnie W C; Yusuf, Rushdia Z; Oki, Toshihiko; Wu, Juwell; Saez, Borja; Wang, Xin; Cook, Colleen; Baryawno, Ninib; Ziller, Michael J; Lee, Eunjung; Gu, Hongcang; Meissner, Alexander; Lin, Charles P; Kharchenko, Peter V; Scadden, David T.

Cell ; 167(5): 1310-1322.e17, 2016 11 17.

Artigo em Inglês | MEDLINE | ID: mdl-27863245

6.

Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia.

Sykes, David B; Kfoury, Youmna S; Mercier, François E; Wawer, Mathias J; Law, Jason M; Haynes, Mark K; Lewis, Timothy A; Schajnovitz, Amir; Jain, Esha; Lee, Dongjun; Meyer, Hanna; Pierce, Kerry A; Tolliday, Nicola J; Waller, Anna; Ferrara, Steven J; Eheim, Ashley L; Stoeckigt, Detlef; Maxcy, Katrina L; Cobert, Julien M; Bachand, Jacqueline; Szekely, Brian A; Mukherjee, Siddhartha; Sklar, Larry A; Kotz, Joanne D; Clish, Clary B; Sadreyev, Ruslan I; Clemons, Paul A; Janzer, Andreas; Schreiber, Stuart L; Scadden, David T.

Cell ; 167(1): 171-186.e15, 2016 Sep 22.

Artigo em Inglês | MEDLINE | ID: mdl-27641501

7.

Not All Created Equal: Lineage Hard-Wiring in the Production of Blood.

Mercier, Francois E; Scadden, David T.

Cell ; 163(7): 1568-70, 2015 Dec 17.

Artigo em Inglês | MEDLINE | ID: mdl-26687347

8.

Author Correction: B lymphocyte-derived acetylcholine limits steady-state and emergency hematopoiesis.

Schloss, Maximilian J; Hulsmans, Maarten; Rohde, David; Lee, I-Hsiu; Severe, Nicolas; Foy, Brody H; Pulous, Fadi E; Zhang, Shuang; Kokkaliaris, Konstantinos D; Frodermann, Vanessa; Courties, Gabriel; Yang, Chongbo; Iwamoto, Yoshiko; Knudsen, Anders Steen; McAlpine, Cameron S; Yamazoe, Masahiro; Schmidt, Stephen P; Wojtkiewicz, Gregory R; Masson, Gustavo Santos; Gustafsson, Karin; Capen, Diane; Brown, Dennis; Higgins, John M; Scadden, David T; Libby, Peter; Swirski, Filip K; Naxerova, Kamila; Nahrendorf, Matthias.

Nat Immunol ; 23(8): 1285, 2022 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-35705799

9.

Nice neighborhood: emerging concepts of the stem cell niche.

Scadden, David T.

Cell ; 157(1): 41-50, 2014 Mar 27.

Artigo em Inglês | MEDLINE | ID: mdl-24679525

10.

Tic-TACs: refreshing hair growth.

Kalaitzidis, Demetrios; Scadden, David T.

Cell ; 157(4): 769-70, 2014 May 08.

Artigo em Inglês | MEDLINE | ID: mdl-24813602

11.

Cell-state-specific metabolic dependency in hematopoiesis and leukemogenesis.

Wang, Ying-Hua; Israelsen, William J; Lee, Dongjun; Yu, Vionnie W C; Jeanson, Nathaniel T; Clish, Clary B; Cantley, Lewis C; Vander Heiden, Matthew G; Scadden, David T.

Cell ; 158(6): 1309-1323, 2014 Sep 11.

Artigo em Inglês | MEDLINE | ID: mdl-25215489

12.

Blood scent.

Silberstein, Lev; Scadden, David T.

Cell ; 155(5): 981-2, 2013 Nov 21.

Artigo em Inglês | MEDLINE | ID: mdl-24267883

13.

Xist RNA is a potent suppressor of hematologic cancer in mice.

Yildirim, Eda; Kirby, James E; Brown, Diane E; Mercier, Francois E; Sadreyev, Ruslan I; Scadden, David T; Lee, Jeannie T.

Cell ; 152(4): 727-42, 2013 Feb 14.

Artigo em Inglês | MEDLINE | ID: mdl-23415223

14.

Genome-wide map of nuclear protein degradation shows NCoR1 turnover as a key to mitochondrial gene regulation.

Catic, André; Suh, Carol Y; Hill, Cedric T; Daheron, Laurence; Henkel, Theresa; Orford, Keith W; Dombkowski, David M; Liu, Tao; Liu, X Shirley; Scadden, David T.

Cell ; 155(6): 1380-95, 2013 Dec 05.

Artigo em Inglês | MEDLINE | ID: mdl-24315104

15.

Deconstructing the complexity of a microenvironmental niche.

Krause, Daniela S; Scadden, David T.

Cell ; 149(1): 16-7, 2012 Mar 30.

Artigo em Inglês | MEDLINE | ID: mdl-22464318

16.

Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells.

Yu, Vionnie W C; Yusuf, Rushdia Z; Oki, Toshihiko; Wu, Juwell; Saez, Borja; Wang, Xin; Cook, Colleen; Baryawno, Ninib; Ziller, Michael J; Lee, Eunjung; Gu, Hongcang; Meissner, Alexander; Lin, Charles P; Kharchenko, Peter V; Scadden, David T.

Cell ; 168(5): 944-945, 2017 02 23.

Artigo em Inglês | MEDLINE | ID: mdl-28235203

17.

Health Consequences of Thymus Removal in Adults.

Kooshesh, Kameron A; Foy, Brody H; Sykes, David B; Gustafsson, Karin; Scadden, David T.

N Engl J Med ; 389(5): 406-417, 2023 Aug 03.

Artigo em Inglês | MEDLINE | ID: mdl-37530823

18.

Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate conditioned Fanconi anemia mice.

Saha, Asim; Palchaudhuri, Rahul; Lanieri, Leanne; Hyzy, Sharon; Riddle, Megan J; Panthera, Jamie; Eide, Cindy; Tolar, Jakub; Panoskaltsis-Mortari, Angela; Gorfinkel, Lev; Tkachev, Victor; Gerdemann, Ulrike; Alvarez-Calderon, Francesca; Palato, Elisa Rojas; MacMillan, Margaret L; Wagner, John E; Kean, Leslie S; Osborn, Mark; Kiem, Hans-Peter; Scadden, David T; Olson, Lisa M; Blazar, Bruce R.

Blood ; 2024 Mar 06.

Artigo em Inglês | MEDLINE | ID: mdl-38447038

19.

AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias.

Sykes, Stephen M; Lane, Steven W; Bullinger, Lars; Kalaitzidis, Demetrios; Yusuf, Rushdia; Saez, Borja; Ferraro, Francesca; Mercier, Francois; Singh, Harshabad; Brumme, Kristina M; Acharya, Sanket S; Scholl, Claudia; Schöll, Claudia; Tothova, Zuzana; Attar, Eyal C; Fröhling, Stefan; DePinho, Ronald A; Armstrong, Scott A; Gilliland, D Gary; Scadden, David T.

Cell ; 146(5): 697-708, 2011 Sep 02.

Artigo em Inglês | MEDLINE | ID: mdl-21884932

20.

C9orf72 suppresses systemic and neural inflammation induced by gut bacteria.

Burberry, Aaron; Wells, Michael F; Limone, Francesco; Couto, Alexander; Smith, Kevin S; Keaney, James; Gillet, Gaëlle; van Gastel, Nick; Wang, Jin-Yuan; Pietilainen, Olli; Qian, Menglu; Eggan, Pierce; Cantrell, Christopher; Mok, Joanie; Kadiu, Irena; Scadden, David T; Eggan, Kevin.

Nature ; 582(7810): 89-94, 2020 06.

Artigo em Inglês | MEDLINE | ID: mdl-32483373

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B lymphocyte-derived acetylcholine limits steady-state and emergency hematopoiesis.

A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia.

Rapid Mobilization Reveals a Highly Engraftable Hematopoietic Stem Cell.

Angiogenin Promotes Hematopoietic Regeneration by Dichotomously Regulating Quiescence of Stem and Progenitor Cells.

Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells.

Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia.

Not All Created Equal: Lineage Hard-Wiring in the Production of Blood.

Author Correction: B lymphocyte-derived acetylcholine limits steady-state and emergency hematopoiesis.

Nice neighborhood: emerging concepts of the stem cell niche.

Tic-TACs: refreshing hair growth.

Cell-state-specific metabolic dependency in hematopoiesis and leukemogenesis.

Blood scent.

Xist RNA is a potent suppressor of hematologic cancer in mice.

Genome-wide map of nuclear protein degradation shows NCoR1 turnover as a key to mitochondrial gene regulation.

Deconstructing the complexity of a microenvironmental niche.

Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells.

Health Consequences of Thymus Removal in Adults.

Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate conditioned Fanconi anemia mice.

AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias.

C9orf72 suppresses systemic and neural inflammation induced by gut bacteria.