Detalhe da pesquisa
1.
Immunohistochemical detection of PAX-FOXO1 fusion proteins in alveolar rhabdomyosarcoma using breakpoint specific monoclonal antibodies.
Mod Pathol
; 34(4): 748-757, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33299109
2.
PAX3-FOXO1: Zooming in on an "undruggable" target.
Semin Cancer Biol
; 50: 115-123, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29146205
3.
Unpeaceful roles of mutant PAX proteins in cancer.
Semin Cell Dev Biol
; 44: 126-34, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26391565
4.
Proteasomal Degradation of the EWS-FLI1 Fusion Protein Is Regulated by a Single Lysine Residue.
J Biol Chem
; 291(52): 26922-26933, 2016 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27875302
5.
FGFR4 signaling couples to Bim and not Bmf to discriminate subsets of alveolar rhabdomyosarcoma cells.
Int J Cancer
; 135(7): 1543-52, 2014 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24550147
6.
Functional Classification of Fusion Proteins in Sarcoma.
Cancers (Basel)
; 16(7)2024 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38611033
7.
The Chromatin Remodeler CHD4 Sustains Ewing Sarcoma Cell Survival by Controlling Global Chromatin Architecture.
Cancer Res
; 84(2): 241-257, 2024 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37963210
8.
Evaluation of the role of AXL in fusion-positive pediatric rhabdomyosarcoma identifies the small-molecule inhibitor bemcentinib (BGB324) as potent chemosensitizer.
Mol Cancer Ther
; 2024 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38471796
9.
Analysis of measurable residual disease by IG/TR gene rearrangements: quality assurance and updated EuroMRD guidelines.
Leukemia
; 2024 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38744919
10.
Elimusertib has Antitumor Activity in Preclinical Patient-Derived Pediatric Solid Tumor Models.
Mol Cancer Ther
; 23(4): 507-519, 2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38159110
11.
Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study.
Blood
; 118(8): 2077-84, 2011 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-21719599
12.
Genomic and Epigenetic Changes Drive Aberrant Skeletal Muscle Differentiation in Rhabdomyosarcoma.
Cancers (Basel)
; 15(10)2023 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37345159
13.
Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance.
Sci Adv
; 9(6): eade9238, 2023 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36753540
14.
PAX3-FOXO1 uses its activation domain to recruit CBP/P300 and shape RNA Pol2 cluster distribution.
Nat Commun
; 14(1): 8361, 2023 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38102136
15.
Adult Low-Hypodiploid Acute Lymphoblastic Leukemia Emerges from Preleukemic TP53-Mutant Clonal Hematopoiesis.
Blood Cancer Discov
; 4(2): 134-149, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36630200
16.
MYOD-SKP2 axis boosts tumorigenesis in fusion negative rhabdomyosarcoma by preventing differentiation through p57Kip2 targeting.
Nat Commun
; 14(1): 8373, 2023 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38102140
17.
Small-molecule screen identifies modulators of EWS/FLI1 target gene expression and cell survival in Ewing's sarcoma.
Int J Cancer
; 131(9): 2153-64, 2012 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22323082
18.
Inhibition of HDACs reduces Ewing sarcoma tumor growth through EWS-FLI1 protein destabilization.
Neoplasia
; 27: 100784, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35366465
19.
CRISPR activation screen identifies TGFß-associated PEG10 as a crucial tumor suppressor in Ewing sarcoma.
Sci Rep
; 12(1): 10671, 2022 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35739280
20.
Molecular testing of rhabdomyosarcoma in clinical trials to improve risk stratification and outcome: A consensus view from European paediatric Soft tissue sarcoma Study Group, Children's Oncology Group and Cooperative Weichteilsarkom-Studiengruppe.
Eur J Cancer
; 172: 367-386, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35839732