Detalhe da pesquisa
1.
Discovery of a highly selective chemical inhibitor of matrix metalloproteinase-9 (MMP-9) that allosterically inhibits zymogen activation.
J Biol Chem
; 292(43): 17963-17974, 2017 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28860188
2.
Identification and structure activity relationships of quinoline tertiary alcohol modulators of RORγt.
Bioorg Med Chem Lett
; 27(9): 2047-2057, 2017 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28318945
3.
6-Substituted quinolines as RORγt inverse agonists.
Bioorg Med Chem Lett
; 27(23): 5277-5283, 2017 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29079472
4.
A novel fluorogenic substrate for the measurement of endothelial lipase activity.
J Lipid Res
; 52(2): 374-82, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21062953
5.
Enhancing recombinant protein quality and yield by protein stability profiling.
J Biomol Screen
; 12(3): 418-28, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17438070
6.
2-Hydroxy-4,6-diamino-[1,3,5]triazines: a novel class of VEGF-R2 (KDR) tyrosine kinase inhibitors.
J Med Chem
; 48(6): 1717-20, 2005 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-15771417
7.
Screening and characterization of human monoglyceride lipase active site inhibitors using orthogonal binding and functional assays.
J Biomol Screen
; 17(5): 629-40, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22496098
8.
Protein thermal shifts to identify low molecular weight fragments.
Methods Enzymol
; 493: 277-98, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21371595
9.
Crystal structure of a soluble form of human monoglyceride lipase in complex with an inhibitor at 1.35 Å resolution.
Protein Sci
; 20(4): 670-83, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21308848
10.
Crystal structure of the tyrosine kinase domain of colony-stimulating factor-1 receptor (cFMS) in complex with two inhibitors.
J Biol Chem
; 282(6): 4094-101, 2007 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-17132624
11.
Protein engineering of the colony-stimulating factor-1 receptor kinase domain for structural studies.
J Biol Chem
; 282(6): 4085-93, 2007 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-17132625