Detalhe da pesquisa
1.
A novel glycoengineered bispecific antibody format for targeted inhibition of epidermal growth factor receptor (EGFR) and insulin-like growth factor receptor type I (IGF-1R) demonstrating unique molecular properties.
J Biol Chem
; 289(27): 18693-706, 2014 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24841203
2.
Development of tetravalent IgG1 dual targeting IGF-1R-EGFR antibodies with potent tumor inhibition.
Arch Biochem Biophys
; 526(2): 206-18, 2012 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22464987
3.
A human cytokine/single-chain antibody fusion protein for simultaneous delivery of GM-CSF and IL-2 to Ep-CAM overexpressing tumor cells.
Cancer Immun
; 6: 4, 2006 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-16483188
4.
XGFR*, a novel affinity-matured bispecific antibody targeting IGF-1R and EGFR with combined signaling inhibition and enhanced immune activation for the treatment of pancreatic cancer.
MAbs
; 8(4): 811-27, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26984378
5.
Antitumor activity of a dual cytokine/single-chain antibody fusion protein for simultaneous delivery of GM-CSF and IL-2 to Ep-CAM expressing tumor cells.
J Immunother
; 29(5): 477-88, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16971804