Detalhe da pesquisa
1.
Active Site Crowding of Cytochrome P450 3A4 as a Strategy To Alter Its Selectivity.
Chembiochem
; 18(3): 248-252, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27897366
2.
Discovery of novel small-molecule antagonists for GluK2.
Bioorg Med Chem Lett
; 25(11): 2416-20, 2015 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25913117
3.
Ex vivo drug testing of patient-derived lung organoids to predict treatment responses for personalized medicine.
Lung Cancer
; 190: 107533, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38520909
4.
Pharmacological characterization of a structural hybrid P2X7R antagonist using ATP and LL-37.
Eur J Pharmacol
; 914: 174667, 2022 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34863711
5.
Trishomocubane as a scaffold for the development of selective dopamine transporter (DAT) ligands.
Bioorg Med Chem Lett
; 21(1): 38-41, 2011 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21146989
6.
A Series of 2-((1-Phenyl-1H-imidazol-5-yl)methyl)-1H-indoles as Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors.
ChemMedChem
; 16(14): 2195-2205, 2021 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33759400
7.
Identification of Potent Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors Based on a Phenylimidazole Scaffold.
ACS Med Chem Lett
; 9(2): 131-136, 2018 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29456801
8.
Discovery and pharmacological evaluation of a novel series of adamantyl cyanoguanidines as P2X7 receptor antagonists.
Eur J Med Chem
; 130: 433-439, 2017 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28279849
9.
3-Oxo-hexahydro-1H-isoindole-4-carboxylic Acid as a Drug Chiral Bicyclic Scaffold: Structure-Based Design and Preparation of Conformationally Constrained Covalent and Noncovalent Prolyl Oligopeptidase Inhibitors.
J Med Chem
; 59(9): 4221-34, 2016 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26619267
10.
Metabolic Instability of Cyanothiazolidine-Based Prolyl Oligopeptidase Inhibitors: a Structural Assignment Challenge and Potential Medicinal Chemistry Implications.
ChemMedChem
; 10(7): 1174-83, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26018317