Detalhe da pesquisa
1.
Inhibitors of protein disulfide isomerase suppress apoptosis induced by misfolded proteins.
Nat Chem Biol
; 6(12): 900-6, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21079601
2.
CRISPR/Cas9 directed to the Ube3a antisense transcript improves Angelman syndrome phenotype in mice.
J Clin Invest
; 131(5)2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33411694
3.
Inhibition of c-Jun kinase provides neuroprotection in a model of Alzheimer's disease.
Neurobiol Dis
; 39(3): 311-7, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20451607
4.
L1 and NCAM adhesion molecules as signaling coreceptors in neuronal migration and process outgrowth.
Curr Opin Neurobiol
; 18(3): 245-50, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18760361
5.
Chd8 haploinsufficiency impairs early brain development and protein homeostasis later in life.
Mol Autism
; 11(1): 74, 2020 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33023670
6.
A methyl-CpG-binding protein 2-enhanced green fluorescent protein reporter mouse model provides a new tool for studying the neuronal basis of Rett syndrome.
Neuroreport
; 19(4): 393-8, 2008 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-18287934
7.
PIK3CA missense mutations promote glioblastoma pathogenesis, but do not enhance targeted PI3K inhibition.
PLoS One
; 13(7): e0200014, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29975751
8.
Tumor-homing cytotoxic human induced neural stem cells for cancer therapy.
Sci Transl Med
; 9(375)2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28148846
9.
Genomic profiles of low-grade murine gliomas evolve during progression to glioblastoma.
Neuro Oncol
; 19(9): 1237-1247, 2017 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28398584
10.
Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma.
Neuro Oncol
; 19(11): 1469-1480, 2017 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28379424
11.
Correction to: Chd8 haploinsufficiency impairs early brain development and protein homeostasis later in life.
Mol Autism
; 12(1): 33, 2021 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33964984
12.
Reactive astrocytes potentiate tumor aggressiveness in a murine glioma resection and recurrence model.
Neuro Oncol
; 18(12): 1622-1633, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27298311
13.
Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation but resistant to temozolomide.
Neuro Oncol
; 18(7): 962-73, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26826202
14.
Adhesion molecule L1 stimulates neuronal migration through Vav2-Pak1 signaling.
Neuroreport
; 15(18): 2791-4, 2004 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-15597056
15.
Modeling astrocytoma pathogenesis in vitro and in vivo using cortical astrocytes or neural stem cells from conditional, genetically engineered mice.
J Vis Exp
; (90): e51763, 2014 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25146643
16.
Cooperativity between MAPK and PI3K signaling activation is required for glioblastoma pathogenesis.
Neuro Oncol
; 15(10): 1317-29, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23814263
17.
Genetically engineered mouse models of diffuse gliomas.
Brain Res Bull
; 88(1): 72-9, 2012 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21684324
18.
Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B.
J Med Chem
; 55(21): 9312-30, 2012 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22998443
19.
Reinduction of ErbB2 in astrocytes promotes radial glial progenitor identity in adult cerebral cortex.
Genes Dev
; 21(24): 3258-71, 2007 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18079173
20.
Generation and characterization of brain lipid-binding protein promoter-based transgenic mouse models for the study of radial glia.
Glia
; 53(4): 345-51, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16288463