Detalhe da pesquisa
1.
Protein therapeutics and their lessons: Expect the unexpected when inhibiting the multi-protein cascade of the complement system.
Immunol Rev
; 313(1): 376-401, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36398537
2.
Triple-fusion protein (TriFu): A potent, targeted, enzyme-like inhibitor of all three complement activation pathways.
J Biol Chem
; 300(4): 105784, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38401844
3.
The Complement-Targeted Inhibitor Mini-FH Protects against Experimental Periodontitis via Both C3-Dependent and C3-Independent Mechanisms.
J Immunol
; 211(3): 453-461, 2023 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37306457
4.
Gliosis-dependent expression of complement factor H truncated variants attenuates retinal neurodegeneration following ischemic injury.
J Neuroinflammation
; 21(1): 56, 2024 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38388518
5.
Complement and the prothrombotic state.
Blood
; 139(13): 1954-1972, 2022 03 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-34415298
6.
Upregulation of Checkpoint Ligand Programmed Death-Ligand 1 in Patients with Paroxysmal Nocturnal Hemoglobinuria Explained by Proximal Complement Activation.
J Immunol
; 208(5): 1248-1258, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35173033
7.
Complement inhibition at the level of C3 or C5: mechanistic reasons for ongoing terminal pathway activity.
Blood
; 137(4): 443-455, 2021 01 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33507296
8.
Human α-Defensin-6 Neutralizes Clostridioides difficile Toxins TcdA and TcdB by Direct Binding.
Int J Mol Sci
; 23(9)2022 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35562899
9.
It's all about complement balance, again.
Blood
; 143(11): 949-951, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38483408
10.
Self versus Nonself Discrimination by the Soluble Complement Regulators Factor H and FHL-1.
J Immunol
; 202(7): 2082-2094, 2019 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30745459
11.
Complement therapeutic strategies in trauma, hemorrhagic shock and systemic inflammation - closing Pandora's box?
Semin Immunol
; 28(3): 278-84, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27157701
12.
Chrysosplenol d, a Flavonol from Artemisia annua, Induces ERK1/2-Mediated Apoptosis in Triple Negative Human Breast Cancer Cells.
Int J Mol Sci
; 21(11)2020 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32521698
13.
Protection of host cells by complement regulators.
Immunol Rev
; 274(1): 152-171, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27782321
14.
Incomplete inhibition by eculizumab: mechanistic evidence for residual C5 activity during strong complement activation.
Blood
; 129(8): 970-980, 2017 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28028023
15.
Biophysical analysis of sialic acid recognition by the complement regulator Factor H.
Glycobiology
; 28(10): 765-773, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29982679
16.
Complement activation by human red blood cell antibodies: hemolytic potential of antibodies and efficacy of complement inhibitors assessed by a sensitive flow cytometric assay.
Transfusion
; 58(12): 2992-3002, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30367826
17.
Increased PD-L1 surface expression on peripheral blood granulocytes and monocytes after vaccination with SARS-CoV2 mRNA or vector vaccine.
Clin Chem Lab Med
; 61(1): e17-e19, 2023 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36245120
18.
Comparative Analysis of Novel Complement-Targeted Inhibitors, MiniFH, and the Natural Regulators Factor H and Factor H-like Protein 1 Reveal Functional Determinants of Complement Regulation.
J Immunol
; 196(2): 866-76, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26643478
19.
Recruitment of Factor H as a Novel Complement Evasion Strategy for Blood-Stage Plasmodium falciparum Infection.
J Immunol
; 196(3): 1239-48, 2016 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26700768
20.
Complement C3dg-mediated erythrophagocytosis: implications for paroxysmal nocturnal hemoglobinuria.
Blood
; 126(7): 891-4, 2015 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-26082452