Detalhe da pesquisa
1.
Ectodomain shedding of CD99 within highly conserved regions is mediated by the metalloprotease meprin ß and promotes transendothelial cell migration.
FASEB J
; 31(3): 1226-1237, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28003343
2.
The intact Kunitz domain protects the amyloid precursor protein from being processed by matriptase-2.
Biol Chem
; 397(8): 777-90, 2016 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27078672
3.
Tetraspanin 8 is an interactor of the metalloprotease meprin ß within tetraspanin-enriched microdomains.
Biol Chem
; 2016 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27180357
4.
Tetraspanin 8 is an interactor of the metalloprotease meprin ß within tetraspanin-enriched microdomains.
Biol Chem
; 397(9): 857-69, 2016 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27180358
5.
Calcium negatively regulates meprin ß activity and attenuates substrate cleavage.
FASEB J
; 29(8): 3549-57, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25957281
6.
Metalloprotease meprin ß is activated by transmembrane serine protease matriptase-2 at the cell surface thereby enhancing APP shedding.
Biochem J
; 470(1): 91-103, 2015 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26251449
7.
Characterization of the Cancer-Associated Meprin Βeta Variants G45R and G89R.
Front Mol Biosci
; 8: 702341, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34692768
8.
Cancer-associated mutations in the canonical cleavage site do not influence CD99 shedding by the metalloprotease meprin ß but alter cell migration in vitro.
Oncotarget
; 8(33): 54873-54888, 2017 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28903388
9.
Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling.
Sci Rep
; 7: 44053, 2017 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28276471
10.
Novel Potent Proline-Based Metalloproteinase Inhibitors: Design, (Radio)Synthesis, and First in Vivo Evaluation as Radiotracers for Positron Emission Tomography.
J Med Chem
; 59(20): 9541-9559, 2016 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27696839