Detalhe da pesquisa
1.
Cell-Autonomous Constitutive gp130 Signaling in T Cells Amplifies TH17 Cell Responses and Causes Severe Lung Inflammation.
J Immunol
; 210(11): 1717-1727, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37058116
2.
The Human GP130 Cytokine Receptor and Its Expression-an Atlas and Functional Taxonomy of Genetic Variants.
J Clin Immunol
; 44(1): 30, 2023 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38133879
3.
Combined hepatocellular-cholangiocarcinoma derives from liver progenitor cells and depends on senescence and IL-6 trans-signaling.
J Hepatol
; 77(6): 1631-1641, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35988690
4.
Functional and structural analysis of cytokine-selective IL6ST defects that cause recessive hyper-IgE syndrome.
J Allergy Clin Immunol
; 148(2): 585-598, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33771552
5.
Cell-autonomous hepatocyte-specific GP130 signaling is sufficient to trigger a robust innate immune response in mice.
J Hepatol
; 74(2): 407-418, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32987028
6.
Degradome of soluble ADAM10 and ADAM17 metalloproteases.
Cell Mol Life Sci
; 77(2): 331-350, 2020 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-31209506
7.
Gut microbiota shape 'inflamm-ageing' cytokines and account for age-dependent decline in DNA damage repair.
Gut
; 69(6): 1064-1075, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31586932
8.
ADAM-Mediated Signalling Pathways in Gastrointestinal Cancer Formation.
Int J Mol Sci
; 21(14)2020 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32698506
9.
IL-6 trans-signaling is essential for the development of hepatocellular carcinoma in mice.
Hepatology
; 65(1): 89-103, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27770462
10.
Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes.
Mol Cell
; 36(2): 326-39, 2009 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-19854140
11.
IL-6 pathway in the liver: From physiopathology to therapy.
J Hepatol
; 64(6): 1403-15, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26867490
12.
Oncogenic deletion mutants of gp130 signal from intracellular compartments.
J Cell Sci
; 127(Pt 2): 341-53, 2014 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24213527
13.
Tetraspanin 8 is an interactor of the metalloprotease meprin ß within tetraspanin-enriched microdomains.
Biol Chem
; 2016 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27180357
14.
Tetraspanin 8 is an interactor of the metalloprotease meprin ß within tetraspanin-enriched microdomains.
Biol Chem
; 397(9): 857-69, 2016 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27180358
15.
Transgenic analysis of the Leishmania MAP kinase MPK10 reveals an auto-inhibitory mechanism crucial for stage-regulated activity and parasite viability.
PLoS Pathog
; 10(9): e1004347, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25232945
16.
Polo-like kinase 2, a novel ADAM17 signaling component, regulates tumor necrosis factor α ectodomain shedding.
J Biol Chem
; 289(5): 3080-93, 2014 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-24338472
17.
Hepatocytes contribute to immune regulation in the liver by activation of the Notch signaling pathway in T cells.
J Immunol
; 191(11): 5574-82, 2013 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24140644
18.
Short-term TNFα shedding is independent of cytoplasmic phosphorylation or furin cleavage of ADAM17.
Biochim Biophys Acta
; 1833(12): 3355-3367, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24135057
19.
gp130 activation is regulated by D2-D3 interdomain connectivity.
Biochem J
; 450(3): 487-96, 2013 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23294003
20.
Tetraspanin15 regulates cellular trafficking and activity of the ectodomain sheddase ADAM10.
Cell Mol Life Sci
; 69(17): 2919-32, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22446748