Detalhe da pesquisa
1.
PHD1-3 oxygen sensors in vivo-lessons learned from gene deletions.
Pflugers Arch
; 2024 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38509356
2.
Evolution of hypoxia and hypoxia-inducible factor asparaginyl hydroxylase regulation in chronic kidney disease.
Nephrol Dial Transplant
; 38(10): 2276-2288, 2023 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37096392
3.
Fount, fate, features, and function of renal erythropoietin-producing cells.
Pflugers Arch
; 474(8): 783-797, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35750861
4.
OTUB1 regulates lung development, adult lung tissue homeostasis, and respiratory control.
FASEB J
; 35(12): e22039, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34793600
5.
The Deubiquitinase OTUB1 Is a Key Regulator of Energy Metabolism.
Int J Mol Sci
; 23(3)2022 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35163456
6.
HIF hydroxylase inhibitors decrease cellular oxygen consumption depending on their selectivity.
FASEB J
; 34(2): 2344-2358, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31908020
7.
Hypoxia in chronic kidney disease: towards a paradigm shift?
Nephrol Dial Transplant
; 36(10): 1782-1790, 2021 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33895835
8.
Hydroxylase Inhibition Selectively Induces Cell Death in Monocytes.
J Immunol
; 202(5): 1521-1530, 2019 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30700584
9.
Generation of renal Epo-producing cell lines by conditional gene tagging reveals rapid HIF-2 driven Epo kinetics, cell autonomous feedback regulation, and a telocyte phenotype.
Kidney Int
; 95(2): 375-387, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30502050
10.
FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1.
PLoS Biol
; 14(1): e1002347, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26752685
11.
Carbon dioxide-dependent regulation of NF-κB family members RelB and p100 gives molecular insight into CO2-dependent immune regulation.
J Biol Chem
; 292(27): 11561-11571, 2017 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28507099
12.
The functional interplay between the HIF pathway and the ubiquitin system - more than a one-way road.
Exp Cell Res
; 356(2): 152-159, 2017 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28315321
13.
Hypercapnia Suppresses the HIF-dependent Adaptive Response to Hypoxia.
J Biol Chem
; 291(22): 11800-8, 2016 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27044749
14.
Paricalcitol protects against TGF-ß1-induced fibrotic responses in hypoxia and stabilises HIF-α in renal epithelia.
Exp Cell Res
; 330(2): 371-381, 2015 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25107382
15.
Regulation of IL-1ß-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways.
Proc Natl Acad Sci U S A
; 110(46): 18490-5, 2013 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24145445
16.
A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network.
J Cell Sci
; 126(Pt 6): 1454-63, 2013 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23390316
17.
Oxomer- and Reporter Gene-Based Analysis of FIH Activity in Cells.
Methods Mol Biol
; 2755: 249-264, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38319583
18.
Selective Hypoxia-Sensitive Oxomer Formation by FIH Prevents Binding of the NF-κB Inhibitor IκBß to NF-κB Subunits.
Mol Cell Biol
; 44(4): 138-148, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38644795
19.
Hydroxylase-dependent regulation of the NF-κB pathway.
Biol Chem
; 394(4): 479-93, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23362195
20.
An intact canonical NF-κB pathway is required for inflammatory gene expression in response to hypoxia.
J Immunol
; 186(2): 1091-6, 2011 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21149600