Detalhe da pesquisa
1.
The Engineered Lysin, CF-370, is Active Against Antibiotic-Resistant Gram-Negative Pathogens In vitro and Synergizes with Meropenem in Experimental Pseudomonas aeruginosa Pneumonia.
J Infect Dis
; 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38366561
2.
Exebacase in Addition to Standard-of-Care Antibiotics for Staphylococcus aureus Bloodstream Infections and Right-Sided Infective Endocarditis: A Phase 3, Superiority-Design, Placebo-Controlled, Randomized Clinical Trial (DISRUPT).
Clin Infect Dis
; 2024 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38297916
3.
Activity of Exebacase (CF-301) against Biofilms Formed by Staphylococcus epidermidis Strains Isolated from Prosthetic Joint Infections.
Antimicrob Agents Chemother
; 66(8): e0058822, 2022 08 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35861539
4.
Exebacase Is Active In Vitro in Pulmonary Surfactant and Is Efficacious Alone and Synergistic with Daptomycin in a Mouse Model of Lethal Staphylococcus aureus Lung Infection.
Antimicrob Agents Chemother
; 65(9): e0272320, 2021 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34228536
5.
Development of a Broth Microdilution Method for Exebacase Susceptibility Testing.
Antimicrob Agents Chemother
; 65(7): e0258720, 2021 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33903102
6.
Exebacase in Addition to Daptomycin against MRSA.
Antimicrob Agents Chemother
; 65(11): e0012821, 2021 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34398668
7.
Determination of MIC Quality Control Parameters for Exebacase, a Novel Lysin with Antistaphylococcal Activity.
J Clin Microbiol
; 59(7): e0311720, 2021 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33910968
8.
Efficacy assessment of lysin CF-296 in addition to daptomycin or vancomycin against Staphylococcus aureus in the murine thigh infection model.
J Antimicrob Chemother
; 76(10): 2622-2628, 2021 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34223628
9.
Exebacase Demonstrates In Vitro Synergy with a Broad Range of Antibiotics against both Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus.
Antimicrob Agents Chemother
; 64(2)2020 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31712212
10.
Synergistic Activity of Exebacase (CF-301) in Addition to Daptomycin against Staphylococcus aureus in a Neutropenic Murine Thigh Infection Model.
Antimicrob Agents Chemother
; 64(3)2020 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31818816
11.
Effect of the Lysin Exebacase on Cardiac Vegetation Progression in a Rabbit Model of Methicillin-Resistant Staphylococcus aureus Endocarditis as Determined by Echocardiography.
Antimicrob Agents Chemother
; 64(7)2020 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32340988
12.
Postantibiotic and Sub-MIC Effects of Exebacase (Lysin CF-301) Enhance Antimicrobial Activity against Staphylococcus aureus.
Antimicrob Agents Chemother
; 63(6)2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30936103
13.
Lysocins: Bioengineered Antimicrobials That Deliver Lysins across the Outer Membrane of Gram-Negative Bacteria.
Antimicrob Agents Chemother
; 63(6)2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30962344
14.
Antimicrobial Activity of Exebacase (Lysin CF-301) against the Most Common Causes of Infective Endocarditis.
Antimicrob Agents Chemother
; 63(10)2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31332073
15.
The Antistaphylococcal Lysin, CF-301, Activates Key Host Factors in Human Blood To Potentiate Methicillin-Resistant Staphylococcus aureus Bacteriolysis.
Antimicrob Agents Chemother
; 63(4)2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30670427
16.
Exebacase in Addition to Daptomycin Is More Active than Daptomycin or Exebacase Alone in Methicillin-Resistant Staphylococcus aureus Osteomyelitis in Rats.
Antimicrob Agents Chemother
; 63(10)2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31358593
17.
The PlyB Endolysin of Bacteriophage vB_BanS_Bcp1 Exhibits Broad-Spectrum Bactericidal Activity against Bacillus cereus Sensu Lato Isolates.
Appl Environ Microbiol
; 85(9)2019 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30850428
18.
Bacteriophage Lysin CF-301, a Potent Antistaphylococcal Biofilm Agent.
Antimicrob Agents Chemother
; 61(7)2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28461319
19.
Correction for Oh et al., "Development of a Broth Microdilution Method for Exebacase Susceptibility Testing".
Antimicrob Agents Chemother
; 65(10): e0165821, 2021 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34533411
20.
Activity of Lysin CF-296 Alone and in Addition to Daptomycin in a Rat Model of Experimental Methicillin-Resistant Staphylococcus aureus Osteomyelitis.
Antimicrob Agents Chemother
; 65(6)2021 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33722889