Detalhe da pesquisa
1.
Brain and visceral gene editing of mucopolysaccharidosis I mice by nasal delivery of the CRISPR/Cas9 system.
J Gene Med
; 24(4): e3410, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35032067
2.
Optimization of Coumarins Extraction from Pterocaulon balansae by Box-Behnken Design and Anti-Trichomonas vaginalis Activity.
Planta Med
; 87(6): 480-488, 2021 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-33578433
3.
Neonatal nonviral gene editing with the CRISPR/Cas9 system improves some cardiovascular, respiratory, and bone disease features of the mucopolysaccharidosis I phenotype in mice.
Gene Ther
; 27(1-2): 74-84, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31827259
4.
In vitro protective effect of topical nanoemulgels containing Brazilian red propolis benzophenones against UV-induced skin damage.
Photochem Photobiol Sci
; 19(10): 1460-1469, 2020 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33026028
5.
Nasal Administration of Cationic Nanoemulsions as Nucleic Acids Delivery Systems Aiming at Mucopolysaccharidosis Type I Gene Therapy.
Pharm Res
; 35(11): 221, 2018 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30259180
6.
Skin Permeation and Oxidative Protection Effect of Soybean Isoflavones from Topical Nanoemulsions-a Comparative Study of Extracts and Pure Compounds.
AAPS PharmSciTech
; 19(7): 3029-3039, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-30084071
7.
Regulatory Framework, Challenges, and Initial Strategic Planning for Advanced Therapy Products (PTAs) Development in Brazil.
Ther Innov Regul Sci
; 58(1): 21-33, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37815738
8.
Topical Nanoemulsions as Delivery Systems for Green Extracts of Pterocaulon balansae Aiming at the Treatment of Sporotrichosis.
Pharmaceutics
; 16(4)2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38675153
9.
Nasal administration of a temozolomide-loaded thermoresponsive nanoemulsion reduces tumor growth in a preclinical glioblastoma model.
J Control Release
; 355: 343-357, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36731799
10.
Gene editing strategies to treat lysosomal disorders: The example of mucopolysaccharidoses.
Adv Drug Deliv Rev
; 191: 114616, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36356930
11.
Biodistribution of Transplanted Hematopoietic Precursor Cells Injected Through Different Administration Routes in Newborn Mice.
Hum Gene Ther
; 32(9-10): 495-505, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33632008
12.
Gene Therapy of Mucopolysaccharidosis Type I Mice: Repeated Administrations and Safety Assessment of pIDUA/Nanoemulsion Complexes.
Curr Gene Ther
; 21(5): 464-471, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33573568
13.
Chitosan-coated rosmarinic acid nanoemulsion nasal administration protects against LPS-induced memory deficit, neuroinflammation, and oxidative stress in Wistar rats.
Neurochem Int
; 141: 104875, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33039443
14.
An overview of the neuroprotective potential of rosmarinic acid and its association with nanotechnology-based delivery systems: A novel approach to treating neurodegenerative disorders.
Neurochem Int
; 122: 47-58, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30439384
15.
Gene editing of MPS I human fibroblasts by co-delivery of a CRISPR/Cas9 plasmid and a donor oligonucleotide using nanoemulsions as nonviral carriers.
Eur J Pharm Biopharm
; 122: 158-166, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-29122734
16.
Optimization of alginate microcapsules containing cells overexpressing α-l-iduronidase using Box-Behnken design.
Eur J Pharm Sci
; 111: 29-37, 2018 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28882767
17.
In vivo genome editing of mucopolysaccharidosis I mice using the CRISPR/Cas9 system.
J Control Release
; 288: 23-33, 2018 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30170069
18.
Box-Behnken design optimization of mucoadhesive chitosan-coated nanoemulsions for rosmarinic acid nasal delivery-In vitro studies.
Carbohydr Polym
; 199: 572-582, 2018 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30143164
19.
Intra-articular nonviral gene therapy in mucopolysaccharidosis I mice.
Int J Pharm
; 548(1): 151-158, 2018 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29940298
20.
Factors influencing transfection efficiency of pIDUA/nanoemulsion complexes in a mucopolysaccharidosis type I murine model.
Int J Nanomedicine
; 12: 2061-2067, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28352175