Detalhe da pesquisa
1.
Amphiphilic Block Copolymer Nanostructures as a Tunable Delivery Platform: Perspective and Framework for the Future Drug Product Development.
Biomacromolecules
; 25(2): 541-563, 2024 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38240244
2.
Establishment of a Pig Influenza Challenge Model for Evaluation of Monoclonal Antibody Delivery Platforms.
J Immunol
; 205(3): 648-660, 2020 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32591390
3.
SARS-CoV-2 Assays To Detect Functional Antibody Responses That Block ACE2 Recognition in Vaccinated Animals and Infected Patients.
J Clin Microbiol
; 58(11)2020 10 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32855181
4.
Intradermal DNA vaccine delivery using vacuum-controlled, needle-free electroporation.
Mol Ther Nucleic Acids
; 34: 102070, 2023 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38034030
5.
Evaluation of calcineurin/NFAT inhibitor selectivity in primary human Th cells using bar-coding and phospho-flow cytometry.
Cytometry A
; 81(11): 1005-11, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22997026
6.
Prime-boost vaccination regimens with INO-4800 and INO-4802 augment and broaden immune responses against SARS-CoV-2 in nonhuman primates.
Vaccine
; 40(21): 2960-2969, 2022 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35428500
7.
Induction of tier-2 neutralizing antibodies in mice with a DNA-encoded HIV envelope native like trimer.
Nat Commun
; 13(1): 695, 2022 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35121758
8.
Nucleic acid delivery of immune-focused SARS-CoV-2 nanoparticles drives rapid and potent immunogenicity capable of single-dose protection.
Cell Rep
; 38(5): 110318, 2022 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35090597
9.
DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2.
Nat Commun
; 13(1): 5886, 2022 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36202799
10.
Multivalent DNA Vaccines as A Strategy to Combat Multiple Concurrent Epidemics: Mosquito-Borne and Hemorrhagic Fever Viruses.
Viruses
; 13(3)2021 02 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33673603
11.
INO-4800 DNA vaccine induces neutralizing antibodies and T cell activity against global SARS-CoV-2 variants.
NPJ Vaccines
; 6(1): 121, 2021 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34650089
12.
One or two dose regimen of the SARS-CoV-2 synthetic DNA vaccine INO-4800 protects against respiratory tract disease burden in nonhuman primate challenge model.
Vaccine
; 39(34): 4885-4894, 2021 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34253420
13.
Intradermal-delivered DNA vaccine induces durable immunity mediating a reduction in viral load in a rhesus macaque SARS-CoV-2 challenge model.
Cell Rep Med
; 2(10): 100420, 2021 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34604818
14.
Safety and immunogenicity of INO-4800 DNA vaccine against SARS-CoV-2: A preliminary report of an open-label, Phase 1 clinical trial.
EClinicalMedicine
; 31: 100689, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-33392485
15.
A DNA-Launched Nanoparticle Vaccine Elicits CD8+ T-cell Immunity to Promote In Vivo Tumor Control.
Cancer Immunol Res
; 8(11): 1354-1364, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32913042
16.
Protection against Borreliella burgdorferi infection mediated by a synthetically engineered DNA vaccine.
Hum Vaccin Immunother
; 16(9): 2114-2122, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32783701
17.
Active immunoprophylaxis with a synthetic DNA-encoded monoclonal anti-respiratory syncytial virus scFv-Fc fusion protein confers protection against infection and durable activity.
Hum Vaccin Immunother
; 16(9): 2165-2175, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32544376
18.
In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure-Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity.
Adv Sci (Weinh)
; 7(8): 1902802, 2020 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-32328416
19.
Immunogenicity of a DNA vaccine candidate for COVID-19.
Nat Commun
; 11(1): 2601, 2020 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32433465
20.
Optimized Interferon-gamma ELISpot Assay to Measure T Cell Responses in the Guinea Pig Model after Vaccination.
J Vis Exp
; (143)2019 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30735179