Detalhe da pesquisa
1.
Mast cells increase vascular permeability by heparin-initiated bradykinin formation in vivo.
Immunity
; 34(2): 258-68, 2011 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-21349432
2.
IsoQC (QPCTL) knock-out mice suggest differential substrate conversion by glutaminyl cyclase isoenzymes.
Biol Chem
; 397(1): 45-55, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26351917
3.
Screen for alterations of iron related parameters in N-ethyl-N-nitrosourea-treated mice identified mutant lines with increased plasma ferritin levels.
Biometals
; 28(2): 293-306, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25636453
4.
Dual function of the UNC-45b chaperone with myosin and GATA4 in cardiac development.
J Cell Sci
; 125(Pt 16): 3893-903, 2012 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22553207
5.
Glutaminyl cyclase-mediated toxicity of pyroglutamate-beta amyloid induces striatal neurodegeneration.
BMC Neurosci
; 14: 108, 2013 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24083638
6.
Selective hippocampal neurodegeneration in transgenic mice expressing small amounts of truncated Aß is induced by pyroglutamate-Aß formation.
J Neurosci
; 31(36): 12790-801, 2011 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21900558
7.
Glutaminyl cyclase knock-out mice exhibit slight hypothyroidism but no hypogonadism: implications for enzyme function and drug development.
J Biol Chem
; 286(16): 14199-208, 2011 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-21330373
8.
Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in hematological parameters.
Mamm Genome
; 22(9-10): 495-505, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21553221
9.
Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in plasma enzyme activities as novel organ-specific disease models.
Exp Physiol
; 94(4): 412-21, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19151073
10.
N-ethyl-N-nitrosourea-based generation of mouse models for mutant G protein-coupled receptors.
Physiol Genomics
; 26(3): 209-17, 2006 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-16720677
11.
Current methods for high-throughput detection of novel DNA polymorphisms.
Drug Discov Today Technol
; 3(2): 123-9, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-24980398
12.
Random mutagenesis in the mouse as a tool in drug discovery.
Drug Discov Today
; 7(23): 1175-83, 2002 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12547018
13.
The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions.
EMBO Mol Med
; 3(9): 545-58, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21774078
14.
Use of an exon-trapping vector for the evaluation of splice-site mutations.
Mamm Genome
; 18(9): 670-6, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17687606
15.
TRESK two-pore-domain K+ channels constitute a significant component of background potassium currents in murine dorsal root ganglion neurones.
J Physiol
; 585(Pt 3): 867-79, 2007 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17962323
16.
Heterozygous R1101K mutation of the DCTN1 gene in a family with ALS and FTD.
Ann Neurol
; 58(5): 777-80, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16240349
17.
Negative-strand RNA viral vectors: intravenous application of Sendai virus vectors for the systemic delivery of therapeutic genes.
Mol Ther
; 7(2): 210-7, 2003 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-12597909