Detalhe da pesquisa
1.
Extraislet expression of islet antigen boosts T cell exhaustion to partially prevent autoimmune diabetes.
Proc Natl Acad Sci U S A
; 121(6): e2315419121, 2024 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38285952
2.
Altering ß Cell Antigen Exposure to Exhausted CD8+ T Cells Prevents Autoimmune Diabetes in Mice.
J Immunol
; 212(11): 1658-1669, 2024 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38587315
3.
Deficiency of the innate immune adaptor STING promotes autoreactive T cell expansion in NOD mice.
Diabetologia
; 64(4): 878-889, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33483762
4.
Harnessing CD8+ T-cell exhaustion to treat type 1 diabetes.
Immunol Cell Biol
; 99(5): 486-495, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33548057
5.
Analysis of antigen specific T cells in diabetes - Lessons from pre-clinical studies and early clinical trials.
J Autoimmun
; 71: 35-43, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27083395
6.
TIGIT acts as an immune checkpoint upon inhibition of PD1 signaling in autoimmune diabetes.
Front Immunol
; 15: 1370907, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38533515
7.
Interferons limit autoantigen-specific CD8+ T-cell expansion in the non-obese diabetic mouse.
Cell Rep
; 39(4): 110747, 2022 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35476975
8.
Transcriptional reprogramming from innate immune functions to a pro-thrombotic signature by monocytes in COVID-19.
Nat Commun
; 13(1): 7947, 2022 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36572683
9.
Antigen-Specific Regulatory T Cell Therapy in Autoimmune Diseases and Transplantation.
Front Immunol
; 12: 661875, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34054826
10.
Tolerance to Proinsulin-1 Reduces Autoimmune Diabetes in NOD Mice.
Front Immunol
; 12: 645817, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33841427
11.
Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice.
Cell Death Differ
; 25(1): 217-225, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29053141
12.
Perinatal tolerance to proinsulin is sufficient to prevent autoimmune diabetes.
JCI Insight
; 1(10): e86065, 2016 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27699217
13.
p53-upregulated-modulator-of-apoptosis (PUMA) deficiency affects food intake but does not impact on body weight or glucose homeostasis in diet-induced obesity.
Sci Rep
; 6: 23802, 2016 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27033313
14.
BIM Deficiency Protects NOD Mice From Diabetes by Diverting Thymocytes to Regulatory T Cells.
Diabetes
; 64(9): 3229-38, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25948683
15.
Using pancreas tissue slices for in situ studies of islet of Langerhans and acinar cell biology.
Nat Protoc
; 9(12): 2809-22, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25393778
16.
Mouse pancreas tissue slice culture facilitates long-term studies of exocrine and endocrine cell physiology in situ.
PLoS One
; 8(11): e78706, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24223842