Detalhe da pesquisa
1.
DUX4-induced bidirectional HSATII satellite repeat transcripts form intranuclear double-stranded RNA foci in human cell models of FSHD.
Hum Mol Genet
; 28(23): 3997-4011, 2019 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31630170
2.
Facioscapulohumeral dystrophy: activating an early embryonic transcriptional program in human skeletal muscle.
Hum Mol Genet
; 27(R2): R153-R162, 2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29718206
3.
DUX4-induced dsRNA and MYC mRNA stabilization activate apoptotic pathways in human cell models of facioscapulohumeral dystrophy.
PLoS Genet
; 13(3): e1006658, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28273136
4.
Model systems of DUX4 expression recapitulate the transcriptional profile of FSHD cells.
Hum Mol Genet
; 25(20): 4419-4431, 2016 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28171552
5.
KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription.
EMBO J
; 30(8): 1473-84, 2011 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-21448134
6.
Multiple repeat regions within mouse DUX recruit chromatin regulators to facilitate an embryonic gene expression program.
bioRxiv
; 2023 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37034731
7.
Chromatin Reprogramming of In Vitro Fertilized and Somatic Cell Nuclear Transfer Bovine Embryos During Embryonic Genome Activation.
bioRxiv
; 2023 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37090641
8.
p53 convergently activates Dux/DUX4 in embryonic stem cells and in facioscapulohumeral muscular dystrophy cell models.
Nat Genet
; 53(8): 1207-1220, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34267371
9.
DUX4 Suppresses MHC Class I to Promote Cancer Immune Evasion and Resistance to Checkpoint Blockade.
Dev Cell
; 50(5): 658-671.e7, 2019 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31327741
10.
NuRD and CAF-1-mediated silencing of the D4Z4 array is modulated by DUX4-induced MBD3L proteins.
Elife
; 72018 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29533181
11.
BET bromodomain inhibitors and agonists of the beta-2 adrenergic receptor identified in screens for compounds that inhibit DUX4 expression in FSHD muscle cells.
Skelet Muscle
; 7(1): 16, 2017 09 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28870238
12.
Increased DUX4 expression during muscle differentiation correlates with decreased SMCHD1 protein levels at D4Z4.
Epigenetics
; 10(12): 1133-42, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26575099
13.
Corrigendum. Increased DUX4 expression during muscle differentiation correlates with decreased SMCHD1 protein levels at D4Z4.
Epigenetics
; 11(2): 175, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27058812