Detalhe da pesquisa
1.
A gain-of-function mutation in DHT synthesis in castration-resistant prostate cancer.
Cell
; 154(5): 1074-1084, 2013 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-23993097
2.
H3K9 methylation drives resistance to androgen receptor-antagonist therapy in prostate cancer.
Proc Natl Acad Sci U S A
; 119(21): e2114324119, 2022 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35584120
3.
3ßHSD activity saturates at physiological substrate concentrations in intact cells.
Prostate
; 83(13): 1306-1309, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37321973
4.
HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma.
Proc Natl Acad Sci U S A
; 117(4): 2187-2193, 2020 01 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31932420
5.
Sex Hormones and Prostate Cancer.
Annu Rev Med
; 71: 33-45, 2020 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31613683
6.
5α-Reductase Inhibitors Are Associated with Reduced Risk of SARS-CoV-2 Infection: A Matched-Pair, Registry-Based Analysis.
J Urol
; 207(1): 183-189, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34433301
7.
Association of HSD3B1 Genotype and Clinical Outcomes in Postmenopausal Estrogen-Receptor-Positive Breast Cancer.
Ann Surg Oncol
; 29(11): 7194-7201, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35776258
8.
Redirecting abiraterone metabolism to fine-tune prostate cancer anti-androgen therapy.
Nature
; 533(7604): 547-51, 2016 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27225130
9.
Benefits of Airway Androgen Receptor Expression in Human Asthma.
Am J Respir Crit Care Med
; 204(3): 285-293, 2021 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33779531
10.
Uptake of high-density lipoprotein by scavenger receptor class B type 1 is associated with prostate cancer proliferation and tumor progression in mice.
J Biol Chem
; 295(24): 8252-8261, 2020 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32358065
11.
Targeting backdoor androgen synthesis through AKR1C3 inhibition: A presurgical hormonal ablative neoadjuvant trial in high-risk localized prostate cancer.
Prostate
; 81(7): 418-426, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33755225
12.
Androgen Deprivation Therapy in Men with Prostate Cancer Does Not Affect Risk of Infection with SARS-CoV-2.
J Urol
; 205(2): 441-443, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32897764
13.
Conversion of abiraterone to D4A drives anti-tumour activity in prostate cancer.
Nature
; 523(7560): 347-51, 2015 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26030522
14.
New insights into genetic susceptibility of COVID-19: an ACE2 and TMPRSS2 polymorphism analysis.
BMC Med
; 18(1): 216, 2020 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32664879
15.
Loss of dihydrotestosterone-inactivation activity promotes prostate cancer castration resistance detectable by functional imaging.
J Biol Chem
; 293(46): 17829-17837, 2018 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30262668
16.
A PK/PD study of Delta-4 abiraterone metabolite in metastatic castration-resistant prostate cancer patients.
Pharmacol Res
; 136: 56-61, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30142421
18.
ASO Author Reflections: Inheritance of Adrenal Permissive HSD3B1 Genotype Negatively Impacts Outcomes in Hormone Receptor-Positive Postmenopausal Breast Cancer.
Ann Surg Oncol
; 29(11): 7202-7203, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35819571
19.
ASO Visual Abstract: Association of HSD3B1 Genotype and Clinical Outcomes in Postmenopausal Estrogen Receptor-Positive Breast Cancer.
Ann Surg Oncol
; 29(11): 7204-7205, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35980550
20.
HSD3B1 and resistance to androgen-deprivation therapy in prostate cancer: a retrospective, multicohort study.
Lancet Oncol
; 17(10): 1435-1444, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27575027