Detalhe da pesquisa
1.
From intuition to AI: evolution of small molecule representations in drug discovery.
Brief Bioinform
; 25(1)2023 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38033290
2.
Phenonaut: multiomics data integration for phenotypic space exploration.
Bioinformatics
; 39(4)2023 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36944259
3.
CLAffinity: A Software Tool for Identification of Optimum Ligand Affinity for Competition-Based Primary Screens.
J Chem Inf Model
; 62(10): 2264-2268, 2022 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35442032
4.
PyBindingCurve, Simulation, and Curve Fitting to Complex Binding Systems at Equilibrium.
J Chem Inf Model
; 61(6): 2911-2915, 2021 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34006095
5.
Real-time tracking of complex ubiquitination cascades using a fluorescent confocal on-bead assay.
BMC Biol
; 16(1): 88, 2018 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30097011
6.
High-throughput chemical screening for antivirulence developmental phenotypes in Trypanosoma brucei.
Eukaryot Cell
; 13(3): 412-26, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24442893
7.
Identification and X-ray co-crystal structure of a small-molecule activator of LFA-1-ICAM-1 binding.
Angew Chem Int Ed Engl
; 53(17): 4322-6, 2014 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24692345
8.
CSBB-ConeExclusion, adapting structure based solution virtual screening to libraries on solid support.
J Chem Inf Model
; 53(12): 3156-62, 2013 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24266324
9.
EDULISS: a small-molecule database with data-mining and pharmacophore searching capabilities.
Nucleic Acids Res
; 39(Database issue): D1042-8, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21051336
10.
Evolution and impact of high content imaging.
SLAS Discov
; 2023 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37666456
11.
Discovery of a new class of inhibitors for the protein arginine deiminase type 4 (PAD4) by structure-based virtual screening.
BMC Bioinformatics
; 13 Suppl 17: S4, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23282142
12.
Chemical Interrogation of Nuclear Size Identifies Compounds with Cancer Cell Line-Specific Effects on Migration and Invasion.
ACS Chem Biol
; 17(3): 680-700, 2022 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35199530
13.
A two-step resin based approach to reveal survivin-selective fluorescent probes.
RSC Chem Biol
; 2(1): 181-186, 2021 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34458780
14.
Quantitative Microdialysis: Experimental Protocol and Software for Small Molecule Protein Affinity Determination and for Exclusion of Compounds with Poor Physicochemical Properties.
Methods Protoc
; 3(3)2020 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32751503
15.
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D.
Nat Commun
; 11(1): 499, 2020 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31980649
16.
PuLSE: Quality control and quantification of peptide sequences explored by phage display libraries.
PLoS One
; 13(2): e0193332, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29474422
17.
Diclofenac Identified as a Kynurenine 3-Monooxygenase Binder and Inhibitor by Molecular Similarity Techniques.
ACS Omega
; 3(3): 2564-2568, 2018 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-30023839
18.
UFSRAT: Ultra-fast Shape Recognition with Atom Types--the discovery of novel bioactive small molecular scaffolds for FKBP12 and 11ßHSD1.
PLoS One
; 10(2): e0116570, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25659145
19.
Inhibition of the ERCC1-XPF structure-specific endonuclease to overcome cancer chemoresistance.
DNA Repair (Amst)
; 31: 19-28, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25956741
20.
11ß-Hydroxysteroid dehydrogenase type 1 contributes to the balance between 7-keto- and 7-hydroxy-oxysterols in vivo.
Biochem Pharmacol
; 86(1): 146-53, 2013 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23415904