RESUMO
Our objective was to review clinical presentation, treatment protocol used and its efficacy and effectiveness in patients of grey zone lymphoma during last 5 years at our centre. A retrospective chart review of children below 18 years of age was done from 2011 to 2016. A proforma was devised for this purpose and the findings of cases detected during the specified period were noted over it. We treated 4 cases, all with a diagnosis of Grey Zone Lymphoma of ages 13, 13, 15 and 7 years at presentation and all were males. Two patients had stage II and the other two had stage III disease. None had a mediastinal mass. All patients were treated according to UKCCSG NHL guidelines. Tumour lysis syndrome was not observed in any child. All tolerated chemotherapy very well and achieved complete remission. No patient died of the disease or any complication and all are well on their latest follow ups. To conclude from excellent outcomes in our case series, we recommend that children with Grey Zone Lymphoma should be treated according to Non-Hodgkin Lymphoma treatment guidelines. However we need to have more prospective studies, so that treatment guidelines can be established.