1.
J Acquir Immune Defic Syndr
; 74(1): 112-116, 2017 Jan 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27532476
RESUMO
HIV Prevention Trials Network 052 demonstrated that antiretroviral therapy (ART) prevents HIV transmission in serodiscordant couples. HIV from index-partner pairs was analyzed to determine the genetic linkage status of partner infections. Forty-six infections were classified as linked, indicating that the index was the likely source of the partner's infection. Lack of viral suppression and higher index viral load were associated with linked infection. Eight linked infections were diagnosed after the index started ART: 4 near the time of ART initiation and 4 after ART failure. Linked infections were not observed when the index participant was stably suppressed on ART.
Assuntos
Fármacos Anti-HIV/administração & dosagem , Quimioprevenção/métodos , Transmissão de Doença Infecciosa/prevenção & controle , Infecções por HIV/prevenção & controle , Estudos de Coortes , Feminino , Humanos , Masculino , Resultado do Tratamento
2.
Artigo
em Inglês
| ARCA
| ID: arc-23278