Detalhe da pesquisa
1.
Fatty acid oxidation participates in resistance to nutrient-depleted environments in the insect stages of Trypanosoma cruzi.
PLoS Pathog
; 17(4): e1009495, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33819309
2.
Abnormal sterol-induced cell wall glucan deficiency in yeast is due to impaired glucan synthase transport to the plasma membrane.
Biochem J
; 2020 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33094814
3.
Trypanosoma cruzi synthesizes proline via a Δ1-pyrroline-5-carboxylate reductase whose activity is fine-tuned by NADPH cytosolic pools.
Biochem J
; 477(10): 1827-1845, 2020 05 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32315030
4.
Dual inhibition of glutaminase and carnitine palmitoyltransferase decreases growth and migration of glutaminase inhibition-resistant triple-negative breast cancer cells.
J Biol Chem
; 294(24): 9342-9357, 2019 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31040181
5.
A Fluorinated Phenylbenzothiazole Arrests the Trypanosoma cruzi Cell Cycle and Diminishes the Infection of Mammalian Host Cells.
Antimicrob Agents Chemother
; 64(2)2020 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31712204
6.
Glutamine Analogues Impair Cell Proliferation, the Intracellular Cycle and Metacyclogenesis in Trypanosoma cruzi.
Molecules
; 25(7)2020 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32252252
7.
In Vitro Cellular Division of Trypanosoma abeli Reveals Two Pathways for Organelle Replication.
J Eukaryot Microbiol
; 66(3): 385-392, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30076737
8.
Diminished Prolinemia in Chronic Chagasic Patients: A New Clue for Disease Pathology?
Molecules
; 24(17)2019 Aug 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31480397
9.
Metabolomic profiling reveals a finely tuned, starvation-induced metabolic switch in Trypanosoma cruzi epimastigotes.
J Biol Chem
; 292(21): 8964-8977, 2017 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28356355
10.
The Non-Canonical Substrates of Trypanosoma cruzi Tyrosine and Aspartate Aminotransferases: Branched-Chain Amino Acids.
J Eukaryot Microbiol
; 65(1): 70-76, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28618210
11.
Development and in vitro/in vivo evaluation of a novel benznidazole liquid dosage form using a quality-by-design approach.
Trop Med Int Health
; 22(12): 1514-1522, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28944986
12.
An Aromatic Diamidine That Targets Kinetoplast DNA, Impairs the Cell Cycle in Trypanosoma cruzi, and Diminishes Trypomastigote Release from Infected Mammalian Host Cells.
Antimicrob Agents Chemother
; 60(10): 5867-77, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27431229
13.
The Uptake of GABA in Trypanosoma cruzi.
J Eukaryot Microbiol
; 62(5): 629-36, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25851259
14.
Cysteine synthase: multiple structures of a key enzyme in cysteine synthesis and a potential drug target for Chagas disease and leishmaniasis.
Acta Crystallogr D Struct Biol
; 79(Pt 6): 518-530, 2023 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37204818
15.
Navigating the boundaries between metabolism and epigenetics in trypanosomes.
Trends Parasitol
; 39(8): 682-695, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37349193
16.
Assignment of putative functions to membrane "hypothetical proteins" from the Trypanosoma cruzi genome.
J Membr Biol
; 245(3): 125-9, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22354180
17.
Proteome and morphological analysis show unexpected differences between promastigotes of Leishmania amazonensis PH8 and LV79 strains.
PLoS One
; 17(8): e0271492, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35998173
18.
An aromatic imidazoline derived from chloroquinoline triggers cell cycle arrest and inhibits with high selectivity the Trypanosoma cruzi mammalian host-cells infection.
PLoS Negl Trop Dis
; 15(11): e0009994, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34843481
19.
Dichloroacetate and Pyruvate Metabolism: Pyruvate Dehydrogenase Kinases as Targets Worth Investigating for Effective Therapy of Toxoplasmosis.
mSphere
; 6(1)2021 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33408226
20.
Chagas' disease: an update on immune mechanisms and therapeutic strategies.
J Cell Mol Med
; 14(6B): 1373-84, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20070438