Detalhe da pesquisa
1.
Effect of mutation order on myeloproliferative neoplasms.
N Engl J Med
; 372(7): 601-612, 2015 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25671252
2.
JAK2V617F promotes replication fork stalling with disease-restricted impairment of the intra-S checkpoint response.
Proc Natl Acad Sci U S A
; 111(42): 15190-5, 2014 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25288776
3.
JAK2V617F homozygosity drives a phenotypic switch in myeloproliferative neoplasms, but is insufficient to sustain disease.
Blood
; 123(20): 3139-51, 2014 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24692758
4.
Self-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansion.
PLoS Biol
; 11(6): e1001576, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23750118
5.
JAK2V617F homozygosity arises commonly and recurrently in PV and ET, but PV is characterized by expansion of a dominant homozygous subclone.
Blood
; 120(13): 2704-7, 2012 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22898600
6.
Clonal analyses reveal associations of JAK2V617F homozygosity with hematologic features, age and gender in polycythemia vera and essential thrombocythemia.
Haematologica
; 98(5): 718-21, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23633544
7.
STAT1 activation in association with JAK2 exon 12 mutations.
Haematologica
; 101(1): e15-9, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26635038
8.
DNMT3A mutations occur early or late in patients with myeloproliferative neoplasms and mutation order influences phenotype.
Haematologica
; 100(11): e438-42, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26250577
9.
Impaired in vitro erythropoiesis following deletion of the Scl (Tal1) +40 enhancer is largely compensated for in vivo despite a significant reduction in expression.
Mol Cell Biol
; 33(6): 1254-66, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23319051
10.
MicroRNA-101 expression is associated with JAK2V617F activity and regulates JAK2/STAT5 signaling.
Leukemia
; 32(8): 1826-1830, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29483713
11.
Cooperativity of imprinted genes inactivated by acquired chromosome 20q deletions.
J Clin Invest
; 123(5): 2169-82, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23543057