Detalhe da pesquisa
1.
A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.
Cell
; 171(6): 1437-1452.e17, 2017 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29195078
2.
Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening.
Cell
; 170(3): 577-592.e10, 2017 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28753431
3.
Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL.
Cell
; 150(3): 575-89, 2012 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22863010
4.
A physical and regulatory map of host-influenza interactions reveals pathways in H1N1 infection.
Cell
; 139(7): 1255-67, 2009 Dec 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-20064372
5.
Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells.
Cell
; 137(5): 821-34, 2009 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-19490892
6.
Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1.
Nature
; 462(7269): 108-12, 2009 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-19847166
7.
A public genome-scale lentiviral expression library of human ORFs.
Nat Methods
; 8(8): 659-61, 2011 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21706014
8.
CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity.
Nature
; 455(7212): 547-51, 2008 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-18794900
9.
Scoring diverse cellular morphologies in image-based screens with iterative feedback and machine learning.
Proc Natl Acad Sci U S A
; 106(6): 1826-31, 2009 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-19188593
10.
Paradoxical Increase of Permeability and Lipophilicity with the Increasing Topological Polar Surface Area within a Series of PRMT5 Inhibitors.
J Med Chem
; 65(18): 12386-12402, 2022 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36069672
11.
SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms.
Sci Rep
; 11(1): 1399, 2021 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33446805
12.
The transcription factor Eyes absent is a protein tyrosine phosphatase.
Nature
; 426(6964): 299-302, 2003 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-14628053
13.
Functional screening identifies miR-315 as a potent activator of Wingless signaling.
Proc Natl Acad Sci U S A
; 104(46): 18151-6, 2007 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-17989227
14.
Tumor Intrinsic Efficacy by SHP2 and RTK Inhibitors in KRAS-Mutant Cancers.
Mol Cancer Ther
; 18(12): 2368-2380, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31439712
15.
New vision from Eyes absent: transcription factors as enzymes.
Trends Genet
; 21(3): 163-71, 2005 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15734575
16.
Generation of High-Throughput Three-Dimensional Tumor Spheroids for Drug Screening.
J Vis Exp
; (139)2018 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30247463
17.
TRPS1 Is a Lineage-Specific Transcriptional Dependency in Breast Cancer.
Cell Rep
; 25(5): 1255-1267.e5, 2018 10 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30380416
18.
Functional dissection of eyes absent reveals new modes of regulation within the retinal determination gene network.
Mol Cell Biol
; 23(17): 5989-99, 2003 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-12917324
19.
Using Drosophila to decipher how mutations associated with human branchio-oto-renal syndrome and optical defects compromise the protein tyrosine phosphatase and transcriptional functions of eyes absent.
Genetics
; 170(2): 687-95, 2005 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15802522
20.
An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.
Nat Genet
; 46(4): 364-70, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24584072