Detalhe da pesquisa
1.
A Newly Discovered Antifibrotic Pathway Regulated by Two Fatty Acid Receptors: GPR40 and GPR84.
Am J Pathol
; 188(5): 1132-1148, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29454750
2.
PBI-4050 via GPR40 activation improves adenine-induced kidney injury in mice.
Clin Sci (Lond)
; 133(14): 1587-1602, 2019 07 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-31308217
3.
PBI-4050 Reduces Stellate Cell Activation and Liver Fibrosis through Modulation of Intracellular ATP Levels and the Liver Kinase B1/AMP-Activated Protein Kinase/Mammalian Target of Rapamycin Pathway.
J Pharmacol Exp Ther
; 367(1): 71-81, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30093459
4.
Silver nanoparticles induce degradation of the endoplasmic reticulum stress sensor activating transcription factor-6 leading to activation of the NLRP-3 inflammasome.
J Biol Chem
; 290(9): 5926-39, 2015 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-25593314
5.
Silver nanoparticles induce irremediable endoplasmic reticulum stress leading to unfolded protein response dependent apoptosis in breast cancer cells.
Apoptosis
; 21(11): 1279-1290, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27586505
6.
Interaction between silver nanoparticles of 20 nm (AgNP20 ) and human neutrophils: induction of apoptosis and inhibition of de novo protein synthesis by AgNP20 aggregates.
J Appl Toxicol
; 34(4): 404-12, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24243556
7.
Damage-associated molecular pattern S100A9 increases bactericidal activity of human neutrophils by enhancing phagocytosis.
J Immunol
; 186(6): 3622-31, 2011 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21325622
8.
Fatty acid mimetic PBI-4547 restores metabolic homeostasis via GPR84 in mice with non-alcoholic fatty liver disease.
Sci Rep
; 10(1): 12778, 2020 07 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32728158
9.
Gold nanoparticles induce apoptosis, endoplasmic reticulum stress events and cleavage of cytoskeletal proteins in human neutrophils.
Toxicol In Vitro
; 31: 12-22, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26551149
10.
Silver nanoparticles of 70 nm and 20 nm affect differently the biology of human neutrophils.
J Immunotoxicol
; 13(3): 375-85, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26619040
11.
Activation of human AML14.3D10 eosinophils by nanoparticles: Modulatory activity on apoptosis and cytokine production.
J Immunotoxicol
; 13(6): 817-826, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27404512
12.
Prolonged cultures of unstimulated human neutrophils lead to the apparition and persistence of rest-in-plate structures (RIPs) recognized by professional phagocytes in vitro and in vivo.
Int J Biochem Cell Biol
; 69: 62-9, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26475019
13.
Silver nanoparticles rapidly induce atypical human neutrophil cell death by a process involving inflammatory caspases and reactive oxygen species and induce neutrophil extracellular traps release upon cell adhesion.
Int Immunopharmacol
; 28(1): 616-25, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26241783
14.
Human S100A9 potentiates IL-8 production in response to GM-CSF or fMLP via activation of a different set of transcription factors in neutrophils.
FEBS Lett
; 588(13): 2141-6, 2014 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24796790
15.
Curcumin inhibits agent-induced human neutrophil functions in vitro and lipopolysaccharide-induced neutrophilic infiltration in vivo.
Int Immunopharmacol
; 17(4): 1101-7, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24157330
16.
Quinoline-3-carboxamides such as tasquinimod are not specific inhibitors of S100A9.
Blood Adv
; 2(10): 1170-1171, 2018 05 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29789315
17.
S100A8 and S100A9 induce cytokine expression and regulate the NLRP3 inflammasome via ROS-dependent activation of NF-κB(1.).
PLoS One
; 8(8): e72138, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23977231
18.
Induction of neutrophil degranulation by S100A9 via a MAPK-dependent mechanism.
J Leukoc Biol
; 87(5): 905-14, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20103766