Detalhe da pesquisa
1.
GPCRs steer Gi and Gs selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors.
Mol Cell
; 82(14): 2681-2695.e6, 2022 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35714614
2.
Structural insights into the lipid and ligand regulation of serotonin receptors.
Nature
; 592(7854): 469-473, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33762731
3.
Pharmacological Characterization and Radiolabeling of VUF15485, a High-Affinity Small-Molecule Agonist for the Atypical Chemokine Receptor ACKR3.
Mol Pharmacol
; 105(4): 301-312, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38346795
4.
PSW-Designer: An Open-Source Computational Platform for the Design and Virtual Screening of Photopharmacological Ligands.
J Chem Inf Model
; 63(21): 6696-6705, 2023 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37831965
5.
Ligand selectivity hotspots in serotonin GPCRs.
Trends Pharmacol Sci
; 44(12): 978-990, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37914598
6.
Structure-Activity Assessment and In-Depth Analysis of Biased Agonism in a Set of Phenylalkylamine 5-HT2A Receptor Agonists.
ACS Chem Neurosci
; 14(15): 2727-2742, 2023 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37474114
7.
Discovery of ß-Arrestin-Biased 25CN-NBOH-Derived 5-HT2A Receptor Agonists.
J Med Chem
; 65(18): 12031-12043, 2022 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36099411