Pesquisa | Biblioteca Virtual em Saúde

1.

Mechanisms of polycomb gene silencing: knowns and unknowns.

Simon, Jeffrey A; Kingston, Robert E.

Nat Rev Mol Cell Biol ; 10(10): 697-708, 2009 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-19738629

2.

Occupying chromatin: Polycomb mechanisms for getting to genomic targets, stopping transcriptional traffic, and staying put.

Simon, Jeffrey A; Kingston, Robert E.

Mol Cell ; 49(5): 808-24, 2013 Mar 07.

Artigo em Inglês | MEDLINE | ID: mdl-23473600

3.

Chromatin compaction at Hox loci: a polycomb tale beyond histone tails.

Simon, Jeffrey A.

Mol Cell ; 38(3): 321-2, 2010 May 14.

Artigo em Inglês | MEDLINE | ID: mdl-20471938

4.

Phase 3 efficacy and safety trial of gadobutrol, a 1.0 molar macrocyclic MR imaging contrast agent, in patients referred for contrast-enhanced MR imaging of the central nervous system.

Gutierrez, Juan E; Rosenberg, Martin; Duhaney, Michael; Simon, Jeffrey A; Brueggenwerth, Guenther; Agris, Jacob M; Knopp, Edmond A.

J Magn Reson Imaging ; 41(3): 788-96, 2015 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-24578298

5.

Inner workings and regulatory inputs that control Polycomb repressive complex 2.

O'Meara, M Maggie; Simon, Jeffrey A.

Chromosoma ; 121(3): 221-34, 2012 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-22349693

6.

Small ubiquitin-like modifier (SUMO) conjugation impedes transcriptional silencing by the polycomb group repressor Sex Comb on Midleg.

Smith, Matthew; Mallin, Daniel R; Simon, Jeffrey A; Courey, Albert J.

J Biol Chem ; 286(13): 11391-400, 2011 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-21278366

7.

Drosophila histone deacetylase-3 controls imaginal disc size through suppression of apoptosis.

Zhu, Changqi C; Bornemann, Douglas J; Zhitomirsky, David; Miller, Ellen L; O'Connor, Michael B; Simon, Jeffrey A.

PLoS Genet ; 4(2): e1000009, 2008 Feb 29.

Artigo em Inglês | MEDLINE | ID: mdl-18454196

8.

Stopping a chromatin enzyme.

Simon, Jeffrey A.

Nat Chem Biol ; 8(11): 875-6, 2012 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-23076065

9.

Alternative ESC and ESC-like subunits of a polycomb group histone methyltransferase complex are differentially deployed during Drosophila development.

Wang, Liangjun; Jahren, Neal; Vargas, Marcus L; Andersen, Erica F; Benes, Judith; Zhang, Junyu; Miller, Ellen L; Jones, Richard S; Simon, Jeffrey A.

Mol Cell Biol ; 26(7): 2637-47, 2006 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-16537908

10.

Programming off and on states in chromatin: mechanisms of Polycomb and trithorax group complexes.

Simon, Jeffrey A; Tamkun, John W.

Curr Opin Genet Dev ; 12(2): 210-8, 2002 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-11893495

11.

Subunit contributions to histone methyltransferase activities of fly and worm polycomb group complexes.

Ketel, Carrie S; Andersen, Erica F; Vargas, Marcus L; Suh, Jinkyo; Strome, Susan; Simon, Jeffrey A.

Mol Cell Biol ; 25(16): 6857-68, 2005 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-16055700

12.

Roles of the EZH2 histone methyltransferase in cancer epigenetics.

Simon, Jeffrey A; Lange, Carol A.

Mutat Res ; 647(1-2): 21-9, 2008 Dec 01.

Artigo em Inglês | MEDLINE | ID: mdl-18723033

13.

A Role for Monomethylation of Histone H3-K27 in Gene Activity in Drosophila.

Wang, Liangjun; Joshi, Preeti; Miller, Ellen L; Higgins, LeeAnn; Slattery, Matthew; Simon, Jeffrey A.

Genetics ; 208(3): 1023-1036, 2018 03.

Artigo em Inglês | MEDLINE | ID: mdl-29242288

14.

Purification and functional characterization of SET8, a nucleosomal histone H4-lysine 20-specific methyltransferase.

Fang, Jia; Feng, Qin; Ketel, Carrie S; Wang, Hengbin; Cao, Ru; Xia, Li; Erdjument-Bromage, Hediye; Tempst, Paul; Simon, Jeffrey A; Zhang, Yi.

Curr Biol ; 12(13): 1086-99, 2002 Jul 09.

Artigo em Inglês | MEDLINE | ID: mdl-12121615

15.

Requirement for sex comb on midleg protein interactions in Drosophila polycomb group repression.

Peterson, Aidan J; Mallin, Daniel R; Francis, Nicole J; Ketel, Carrie S; Stamm, Joyce; Voeller, Rochus K; Kingston, Robert E; Simon, Jeffrey A.

Genetics ; 167(3): 1225-39, 2004 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-15280237

16.

A strand-specific switch in noncoding transcription switches the function of a Polycomb/Trithorax response element.

Herzog, Veronika A; Lempradl, Adelheid; Trupke, Johanna; Okulski, Helena; Altmutter, Christina; Ruge, Frank; Boidol, Bernd; Kubicek, Stefan; Schmauss, Gerald; Aumayr, Karin; Ruf, Marius; Pospisilik, Andrew; Dimond, Andrew; Senergin, Hasene Basak; Vargas, Marcus L; Simon, Jeffrey A; Ringrose, Leonie.

Nat Genet ; 46(9): 973-981, 2014 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-25108384

17.

Elements of the polycomb repressor SU(Z)12 needed for histone H3-K27 methylation, the interface with E(Z), and in vivo function.

Rai, Aswathy N; Vargas, Marcus L; Wang, Liangjun; Andersen, Erica F; Miller, Ellen L; Simon, Jeffrey A.

Mol Cell Biol ; 33(24): 4844-56, 2013 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-24100017

18.

Polycomb group proteins.

Simon, Jeffrey A.

Curr Biol ; 13(3): R79-80, 2003 Feb 04.

Artigo em Inglês | MEDLINE | ID: mdl-12573228

19.

Correction for Wang et al., "Comparative Analysis of Chromatin Binding by Sex Comb on Midleg (SCM) and Other Polycomb Group Repressors at a Drosophila Hox Gene".

Wang, Liangjun; Jahren, Neal; Miller, Ellen L; Ketel, Carrie S; Mallin, Daniel R; Simon, Jeffrey A.

Mol Cell Biol ; 37(15)2017 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-28710118

20.

Comparative analysis of chromatin binding by Sex Comb on Midleg (SCM) and other polycomb group repressors at a Drosophila Hox gene.

Wang, Liangjun; Jahren, Neal; Miller, Ellen L; Ketel, Carrie S; Mallin, Daniel R; Simon, Jeffrey A.

Mol Cell Biol ; 30(11): 2584-93, 2010 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-20351181

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Mechanisms of polycomb gene silencing: knowns and unknowns.

Occupying chromatin: Polycomb mechanisms for getting to genomic targets, stopping transcriptional traffic, and staying put.

Chromatin compaction at Hox loci: a polycomb tale beyond histone tails.

Phase 3 efficacy and safety trial of gadobutrol, a 1.0 molar macrocyclic MR imaging contrast agent, in patients referred for contrast-enhanced MR imaging of the central nervous system.

Inner workings and regulatory inputs that control Polycomb repressive complex 2.

Small ubiquitin-like modifier (SUMO) conjugation impedes transcriptional silencing by the polycomb group repressor Sex Comb on Midleg.

Drosophila histone deacetylase-3 controls imaginal disc size through suppression of apoptosis.

Stopping a chromatin enzyme.

Alternative ESC and ESC-like subunits of a polycomb group histone methyltransferase complex are differentially deployed during Drosophila development.

Programming off and on states in chromatin: mechanisms of Polycomb and trithorax group complexes.

Subunit contributions to histone methyltransferase activities of fly and worm polycomb group complexes.

Roles of the EZH2 histone methyltransferase in cancer epigenetics.

A Role for Monomethylation of Histone H3-K27 in Gene Activity in Drosophila.

Purification and functional characterization of SET8, a nucleosomal histone H4-lysine 20-specific methyltransferase.

Requirement for sex comb on midleg protein interactions in Drosophila polycomb group repression.

A strand-specific switch in noncoding transcription switches the function of a Polycomb/Trithorax response element.

Elements of the polycomb repressor SU(Z)12 needed for histone H3-K27 methylation, the interface with E(Z), and in vivo function.

Polycomb group proteins.

Correction for Wang et al., "Comparative Analysis of Chromatin Binding by Sex Comb on Midleg (SCM) and Other Polycomb Group Repressors at a Drosophila Hox Gene".

Comparative analysis of chromatin binding by Sex Comb on Midleg (SCM) and other polycomb group repressors at a Drosophila Hox gene.