Detalhe da pesquisa
1.
Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier.
Proc Natl Acad Sci U S A
; 110(14): 5422-7, 2013 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23513224
2.
Analysis of cellular and behavioral responses to imiquimod reveals a unique itch pathway in transient receptor potential vanilloid 1 (TRPV1)-expressing neurons.
Proc Natl Acad Sci U S A
; 108(8): 3371-6, 2011 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-21300878
3.
NADPH oxidase 2-derived reactive oxygen species in spinal cord microglia contribute to peripheral nerve injury-induced neuropathic pain.
Proc Natl Acad Sci U S A
; 107(33): 14851-6, 2010 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-20679217
4.
Evidence for two apoptotic pathways in light-induced retinal degeneration.
Nat Genet
; 32(2): 254-60, 2002 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12219089
5.
Synergistic Ca2+ responses by G{alpha}i- and G{alpha}q-coupled G-protein-coupled receptors require a single PLC{beta} isoform that is sensitive to both G{beta}{gamma} and G{alpha}q.
J Biol Chem
; 286(2): 942-51, 2011 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21036901
6.
TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms.
Proc Natl Acad Sci U S A
; 106(27): 11330-5, 2009 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-19564617
7.
G13 is an essential mediator of platelet activation in hemostasis and thrombosis.
Nat Med
; 9(11): 1418-22, 2003 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-14528298
8.
Molecular architecture of Galphao and the structural basis for RGS16-mediated deactivation.
Proc Natl Acad Sci U S A
; 105(17): 6243-8, 2008 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-18434540
9.
Variability in G-protein-coupled signaling studied with microfluidic devices.
Biophys J
; 99(8): 2414-22, 2010 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-20959081
10.
Phospholipase Cbeta 3 mediates the scratching response activated by the histamine H1 receptor on C-fiber nociceptive neurons.
Neuron
; 52(4): 691-703, 2006 Nov 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-17114052
11.
RGS9 modulates dopamine signaling in the basal ganglia.
Neuron
; 38(6): 941-52, 2003 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-12818179
12.
Deactivation of phosphorylated and nonphosphorylated rhodopsin by arrestin splice variants.
J Neurosci
; 26(3): 1036-44, 2006 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-16421323
13.
A versatile approach to multiple gene RNA interference using microRNA-based short hairpin RNAs.
BMC Mol Biol
; 8: 98, 2007 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-17971228
14.
D2 dopamine receptors colocalize regulator of G-protein signaling 9-2 (RGS9-2) via the RGS9 DEP domain, and RGS9 knock-out mice develop dyskinesias associated with dopamine pathways.
J Neurosci
; 25(8): 2157-65, 2005 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-15728856
15.
Prolonged photoresponses and defective adaptation in rods of Gbeta5-/- mice.
J Neurosci
; 23(18): 6965-71, 2003 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-12904457
16.
Group I metabotropic glutamate receptor signaling via Galpha q/Galpha 11 secures the induction of long-term potentiation in the hippocampal area CA1.
J Neurosci
; 22(19): 8379-90, 2002 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12351712
17.
Novel form of adaptation in mouse retinal rods speeds recovery of phototransduction.
J Gen Physiol
; 122(6): 703-12, 2003 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-14610022
18.
Helical shifts generate two distinct conformers in the atomic resolution structure of the CheA phosphotransferase domain from Thermotoga maritima.
J Mol Biol
; 341(5): 1283-94, 2004 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-15321722
19.
Caenorhabditis elegans Galphaq regulates egg-laying behavior via a PLCbeta-independent and serotonin-dependent signaling pathway and likely functions both in the nervous system and in muscle.
Genetics
; 165(4): 1805-22, 2003 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-14704167
20.
Bax is not the heterodimerization partner necessary for sustained anti-photoreceptor-cell-death activity of Bcl-2.
Invest Ophthalmol Vis Sci
; 43(5): 1636-44, 2002 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-11980885