Detalhe da pesquisa
1.
Synthesis, SAR, and atropisomerism of imidazolopyrimidine DPP4 inhibitors.
Bioorg Med Chem Lett
; 20(21): 6273-6, 2010 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20833042
2.
Pyridine amides as potent and selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1.
Bioorg Med Chem Lett
; 18(11): 3168-72, 2008 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18485702
3.
Potent non-nitrile dipeptidic dipeptidyl peptidase IV inhibitors.
Bioorg Med Chem Lett
; 17(23): 6476-80, 2007 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17937986
4.
Discovery and preclinical profile of Saxagliptin (BMS-477118): a highly potent, long-acting, orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.
J Med Chem
; 48(15): 5025-37, 2005 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-16033281
5.
Synthesis of novel potent dipeptidyl peptidase IV inhibitors with enhanced chemical stability: interplay between the N-terminal amino acid alkyl side chain and the cyclopropyl group of alpha-aminoacyl-l-cis-4,5-methanoprolinenitrile-based inhibitors.
J Med Chem
; 47(10): 2587-98, 2004 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-15115400
6.
N-aryl-oxazolidin-2-imine muscle selective androgen receptor modulators enhance potency through pharmacophore reorientation.
J Med Chem
; 52(9): 2794-8, 2009 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-19351168
7.
Diprolyl nitriles as potent dipeptidyl peptidase IV inhibitors.
Bioorg Med Chem Lett
; 15(18): 3992-5, 2005 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16046120