Detalhe da pesquisa
1.
The Microglial Transcriptome of Age-Associated Deep Subcortical White Matter Lesions Suggests a Neuroprotective Response to Blood-Brain Barrier Dysfunction.
Int J Mol Sci
; 25(8)2024 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38674030
2.
Insights into the pathological basis of dementia from population-based neuropathology studies.
Neuropathol Appl Neurobiol
; 49(4): e12923, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37462105
3.
Potential Mechanisms Underlying the Dysfunction of the Blood-Brain Barrier.
Int J Mol Sci
; 24(9)2023 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37175890
4.
Biological and methodological complexities of beta-amyloid peptide: Implications for Alzheimer's disease research.
J Neurochem
; 160(4): 434-453, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34767256
5.
RNA-Seq Profiling of Neutrophil-Derived Microvesicles in Alzheimer's Disease Patients Identifies a miRNA Signature That May Impact Blood-Brain Barrier Integrity.
Int J Mol Sci
; 23(11)2022 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35682592
6.
Persistent DNA damage alters the neuronal transcriptome suggesting cell cycle dysregulation and altered mitochondrial function.
Eur J Neurosci
; 54(9): 6987-7005, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34536321
7.
Histological characterization of interneurons in Alzheimer's disease reveals a loss of somatostatin interneurons in the temporal cortex.
Neuropathology
; 40(4): 336-346, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-32232904
8.
Transcriptomic Analysis of Human Astrocytes In Vitro Reveals Hypoxia-Induced Mitochondrial Dysfunction, Modulation of Metabolism, and Dysregulation of the Immune Response.
Int J Mol Sci
; 21(21)2020 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33126586
9.
Transcriptomic Analysis of Age-Associated Periventricular Lesions Reveals Dysregulation of the Immune Response.
Int J Mol Sci
; 21(21)2020 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33113879
10.
NDRG2 Expression Correlates with Neurofibrillary Tangles and Microglial Pathology in the Ageing Brain.
Int J Mol Sci
; 21(1)2020 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31947996
11.
The Pattern of AQP4 Expression in the Ageing Human Brain and in Cerebral Amyloid Angiopathy.
Int J Mol Sci
; 21(4)2020 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32059400
12.
Neutrophil-Derived Microvesicle Induced Dysfunction of Brain Microvascular Endothelial Cells In Vitro.
Int J Mol Sci
; 20(20)2019 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31652502
13.
Age-Associated mRNA and miRNA Expression Changes in the Blood-Brain Barrier.
Int J Mol Sci
; 20(12)2019 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31242592
14.
Metallothionein-I/II expression associates with the astrocyte DNA damage response and not Alzheimer-type pathology in the aging brain.
Glia
; 66(11): 2316-2323, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30098078
15.
Local volume fraction distributions of axons, astrocytes, and myelin in deep subcortical white matter.
Neuroimage
; 179: 275-287, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29933040
16.
Proteomic and cellular localisation studies suggest non-tight junction cytoplasmic and nuclear roles for occludin in astrocytes.
Eur J Neurosci
; 47(12): 1444-1456, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29738614
17.
Spinal muscular atrophy: Factors that modulate motor neurone vulnerability.
Neurobiol Dis
; 102: 11-20, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28161391
18.
Neuronal DNA damage response-associated dysregulation of signalling pathways and cholesterol metabolism at the earliest stages of Alzheimer-type pathology.
Neuropathol Appl Neurobiol
; 42(2): 167-79, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26095650
19.
A neuronal DNA damage response is detected at the earliest stages of Alzheimer's neuropathology and correlates with cognitive impairment in the Medical Research Council's Cognitive Function and Ageing Study ageing brain cohort.
Neuropathol Appl Neurobiol
; 41(4): 483-96, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25443110
20.
MicroRNA-155 negatively affects blood-brain barrier function during neuroinflammation.
FASEB J
; 28(6): 2551-65, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24604078