Detalhe da pesquisa
1.
Integrated single-cell profiling dissects cell-state-specific enhancer landscapes of human tumor-infiltrating CD8+ T cells.
Mol Cell
; 83(4): 622-636.e10, 2023 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36657444
2.
The immunological Warburg effect: Can a metabolic-tumor-stroma score (MeTS) guide cancer immunotherapy?
Immunol Rev
; 295(1): 187-202, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32157706
3.
Double genetic disruption of lactate dehydrogenases A and B is required to ablate the "Warburg effect" restricting tumor growth to oxidative metabolism.
J Biol Chem
; 293(41): 15947-15961, 2018 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30158244
4.
D-2-Hydroxyglutarate and L-2-Hydroxyglutarate Inhibit IL-12 Secretion by Human Monocyte-Derived Dendritic Cells.
Int J Mol Sci
; 20(3)2019 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30744183
5.
Metabolic plasticity of human T cells: Preserved cytokine production under glucose deprivation or mitochondrial restriction, but 2-deoxy-glucose affects effector functions.
Eur J Immunol
; 45(9): 2504-16, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26114249
6.
The Nonmetabolized ß-Blocker Nadolol Is a Substrate of OCT1, OCT2, MATE1, MATE2-K, and P-Glycoprotein, but Not of OATP1B1 and OATP1B3.
Mol Pharm
; 13(2): 512-9, 2016 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26702643
7.
Antithymocyte Globulin Induces a Tolerogenic Phenotype in Human Dendritic Cells.
Int J Mol Sci
; 17(12)2016 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27973435
8.
Lactic acid delays the inflammatory response of human monocytes.
Biochem Biophys Res Commun
; 457(3): 412-8, 2015 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25582773
9.
Warburg phenotype in renal cell carcinoma: high expression of glucose-transporter 1 (GLUT-1) correlates with low CD8(+) T-cell infiltration in the tumor.
Int J Cancer
; 128(9): 2085-95, 2011 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20607826
10.
Suppression of T-cell responses by tumor metabolites.
Cancer Immunol Immunother
; 60(3): 425-31, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21240484
11.
1,25-dihydroxyvitamin-D3 but not the clinically applied marker 25-hydroxyvitamin-D3 predicts survival after stem cell transplantation.
Bone Marrow Transplant
; 56(2): 419-433, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32855442
12.
The predictive power of CD3+ T cell infiltration of oral squamous cell tumors is limited to non-diabetic patients.
Cancer Lett
; 499: 209-219, 2021 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33276040
13.
Kynurenine induces T cell fat catabolism and has limited suppressive effects in vivo.
EBioMedicine
; 74: 103734, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34875457
14.
Metabolic imbalance of T cells in COVID-19 is hallmarked by basigin and mitigated by dexamethasone.
J Clin Invest
; 131(22)2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34779418
15.
Selective PRMT5 Inhibitors Suppress Human CD8+ T Cells by Upregulation of p53 and Impairment of the AKT Pathway Similar to the Tumor Metabolite MTA.
Mol Cancer Ther
; 19(2): 409-419, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31712395
16.
Complete sequential assignment and secondary structure prediction of the cannulae forming protein CanA from the hyperthermophilic archaeon Pyrodictium abyssi.
Biomol NMR Assign
; 14(1): 141-146, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32052266
17.
Topical Diclofenac Reprograms Metabolism and Immune Cell Infiltration in Actinic Keratosis.
Front Oncol
; 9: 605, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31334125
18.
Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy.
Cell Rep
; 29(1): 135-150.e9, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31577944
19.
Immunometabolism in cancer at a glance.
Dis Model Mech
; 11(8)2018 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30076128
20.
Combined Metabolic Targeting With Metformin and the NSAIDs Diflunisal and Diclofenac Induces Apoptosis in Acute Myeloid Leukemia Cells.
Front Pharmacol
; 9: 1258, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30450049