Detalhe da pesquisa
1.
One-pot synthesis of high molar activity 6-[18F]fluoro-l-DOPA by Cu-mediated fluorination of a BPin precursor.
Org Biomol Chem
; 17(38): 8701-8705, 2019 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31536095
2.
[18F]BTK-1: A Novel Positron Emission Tomography Tracer for Imaging Bruton's Tyrosine Kinase.
Mol Imaging Biol
; 24(5): 830-841, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35482146
3.
Strategies for PET imaging of the receptor for advanced glycation endproducts (RAGE).
J Pharm Anal
; 10(5): 452-465, 2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-33133729
4.
Synthesis of high-molar-activity [18F]6-fluoro-L-DOPA suitable for human use via Cu-mediated fluorination of a BPin precursor.
Nat Protoc
; 15(5): 1742-1759, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32269382
5.
The Discovery of a Novel Phosphodiesterase (PDE) 4B-Preferring Radioligand for Positron Emission Tomography (PET) Imaging.
J Med Chem
; 60(20): 8538-8551, 2017 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28957634
6.
Discovery and Characterization of (R)-6-Neopentyl-2-(pyridin-2-ylmethoxy)-6,7-dihydropyrimido[2,1-c][1,4]oxazin-4(9H)-one (PF-06462894), an Alkyne-Lacking Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator Profiled in both Rat and Nonhuman Primates.
J Med Chem
; 60(18): 7764-7780, 2017 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28817277
7.
Preclinical Evaluation of 18F-PF-05270430, a Novel PET Radioligand for the Phosphodiesterase 2A Enzyme.
J Nucl Med
; 57(9): 1448-53, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27199356
8.
Stoichiometric and catalytic deuterium and tritium labeling of "unactivated" organic substrates with cationic Ir(III) complexes.
Org Lett
; 6(1): 11-3, 2004 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-14703338
9.
Synthesis and Binding Affinities of Novel Re-Containing 7alpha-Substituted Estradiol Complexes: Models for Breast Cancer Imaging Agents.
J Org Chem
; 64(22): 8108-8121, 1999 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-11674724
10.
Discovery and preclinical characterization of 1-methyl-3-(4-methylpyridin-3-yl)-6-(pyridin-2-ylmethoxy)-1H-pyrazolo-[3,4-b]pyrazine (PF470): a highly potent, selective, and efficacious metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator.
J Med Chem
; 57(3): 861-77, 2014 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24392688
11.
Design and selection parameters to accelerate the discovery of novel central nervous system positron emission tomography (PET) ligands and their application in the development of a novel phosphodiesterase 2A PET ligand.
J Med Chem
; 56(11): 4568-79, 2013 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23651455
12.
The synthesis and in vivo evaluation of [18F]PF-9811: a novel PET ligand for imaging brain fatty acid amide hydrolase (FAAH).
Nucl Med Biol
; 39(7): 1058-67, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22571907
13.
Pancreatic beta cell mass PET imaging and quantification with [11C]DTBZ and [18F]FP-(+)-DTBZ in rodent models of diabetes.
Mol Imaging Biol
; 13(5): 973-84, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20824509
14.
Stoichiometric and catalytic H/D incorporation by cationic iridium complexes: a common monohydrido-iridium intermediate.
J Am Chem Soc
; 126(40): 13033-43, 2004 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-15469302
15.
(R)-N-[11C]methyl-3-pyrrolidyl benzilate, a high-affinity reversible radioligand for PET studies of the muscarinic acetylcholine receptor.
Synapse
; 45(1): 31-7, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12112411