Detalhe da pesquisa
1.
Convergent total synthesis of (+)-calcipotriol: A scalable, modular approach to vitamin D analogs.
Proc Natl Acad Sci U S A
; 119(18): e2200814119, 2022 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35476519
2.
Pharmacology of orismilast, a potent and selective PDE4 inhibitor.
J Eur Acad Dermatol Venereol
; 37(4): 721-729, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-36527389
3.
Design and characterization of matrix metalloproteinase-responsive hydrogels for the treatment of inflammatory skin diseases.
Acta Biomater
; 157: 149-161, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36526241
4.
Macrolide Inspired Macrocycles as Modulators of the IL-17A/IL-17RA Interaction.
J Med Chem
; 64(12): 8354-8383, 2021 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34100601
5.
Discovery and Early Clinical Development of Isobutyl 1-[8-Methoxy-5-(1-oxo-3H-isobenzofuran-5-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxylate (LEO 39652), a Novel "Dual-Soft" PDE4 Inhibitor for Topical Treatment of Atopic Dermatitis.
J Med Chem
; 63(23): 14502-14521, 2020 12 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33054196
6.
Mitogen- and stress-activated protein kinase 1 is activated in lesional psoriatic epidermis and regulates the expression of pro-inflammatory cytokines.
J Invest Dermatol
; 126(8): 1784-91, 2006 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16543895
7.
Synthesis and structure-activity relationship of aminobenzophenones. A novel class of p38 MAP kinase inhibitors with high antiinflammatory activity.
J Med Chem
; 46(26): 5651-62, 2003 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-14667219
8.
Detection of fumarate-glutathione adducts in the portal vein blood of rats: evidence for rapid dimethylfumarate metabolism.
Arch Dermatol Res
; 305(5): 447-51, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23525570
9.
Protein expression of TNF-alpha in psoriatic skin is regulated at a posttranscriptional level by MAPK-activated protein kinase 2.
J Immunol
; 176(3): 1431-8, 2006 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16424170