Detalhe da pesquisa
1.
A combined approach of structure-based virtual screening and NMR to interrupt the PD-1/PD-L1 axis: Biphenyl-benzimidazole containing compounds as novel PD-L1 inhibitors.
Arch Pharm (Weinheim)
; 357(3): e2300583, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38110703
2.
Structural and biological characterization of pAC65, a macrocyclic peptide that blocks PD-L1 with equivalent potency to the FDA-approved antibodies.
Mol Cancer
; 22(1): 150, 2023 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37679783
3.
Biphenyl Ether Analogs Containing Pomalidomide as Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction.
Molecules
; 27(11)2022 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35684392
4.
Application of bioorthogonal hetero-Diels-Alder cycloaddition of 5-arylidene derivatives of 1,3-dimethylbarbituric acid and vinyl thioether for imaging inside living cells.
Org Biomol Chem
; 19(27): 6045-6058, 2021 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34137394
5.
PD-L1 Inhibitors: Different Classes, Activities, and Mechanisms of Action.
Int J Mol Sci
; 22(21)2021 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34769226
6.
Germacranolides from Carpesium divaricatum: Some New Data on Cytotoxic and Anti-Inflammatory Activity.
Molecules
; 26(15)2021 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34361797
7.
Multicomponent Peptide Stapling as a Diversity-Driven Tool for the Development of Inhibitors of Protein-Protein Interactions.
Angew Chem Int Ed Engl
; 59(13): 5235-5241, 2020 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31944488
8.
CA-170 - A Potent Small-Molecule PD-L1 Inhibitor or Not?
Molecules
; 24(15)2019 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31374878
9.
Bioactive Macrocyclic Inhibitors of the PD-1/PD-L1 Immune Checkpoint.
Angew Chem Int Ed Engl
; 56(44): 13732-13735, 2017 10 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28881104
10.
MCPIP1 contributes to the toxicity of proteasome inhibitor MG-132 in HeLa cells by the inhibition of NF-κB.
Mol Cell Biochem
; 395(1-2): 253-63, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24992982
11.
Solubilizer Tag Effect on PD-L1/Inhibitor Binding Properties for m-Terphenyl Derivatives.
ACS Med Chem Lett
; 15(1): 36-44, 2024 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38229762
12.
Monocyte chemotactic protein-1-induced protein-1 (MCPIP1) is a novel multifunctional modulator of inflammatory reactions.
Biochim Biophys Acta
; 1823(10): 1905-13, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22771441
13.
Effect of silver nanoparticles on human primary keratinocytes.
Biol Chem
; 394(1): 113-23, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23091270
14.
Effects of the novel mitochondrial protein mimitin in insulin-secreting cells.
Biochem J
; 445(3): 349-59, 2012 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22587331
15.
A study of the interactions between human osteoblast-like cells and polymer composites with functionalized graphene derivatives using 2D correlation spectroscopy (2D-COS).
Spectrochim Acta A Mol Biomol Spectrosc
; 285: 121862, 2023 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36122465
16.
Design, Synthesis, and Biological Evaluation of 2-Hydroxy-4-phenylthiophene-3-carbonitrile as PD-L1 Antagonist and Its Comparison to Available Small Molecular PD-L1 Inhibitors.
J Med Chem
; 66(14): 9577-9591, 2023 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37450644
17.
Early Recognition of the PCL/Fibrous Carbon Nanocomposites Interaction with Osteoblast-like Cells by Raman Spectroscopy.
Nanomaterials (Basel)
; 11(11)2021 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34835654
18.
Terphenyl-Based Small-Molecule Inhibitors of Programmed Cell Death-1/Programmed Death-Ligand 1 Protein-Protein Interaction.
J Med Chem
; 64(15): 11614-11636, 2021 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34313116
19.
Human and mouse PD-L1: similar molecular structure, but different druggability profiles.
iScience
; 24(1): 101960, 2021 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33437940
20.
Resveratrol enhances apoptosis induced by the heterocyclic aromatic amines in p53-wt LoVo cells, but not in p53-deficient HaCaT cells.
Acta Biochim Pol
; 67(4): 605-611, 2020 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33108147