Detalhe da pesquisa
1.
Dose-related differences in the pharmacodynamic and toxicologic response to a novel hyperglycosylated analog of recombinant human erythropoietin in Sprague-Dawley rats with similarly high hematocrit.
Toxicol Pathol
; 42(3): 524-39, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-23674391
2.
Cytokines associated with increased erythropoiesis in Sprague-Dawley rats administered a novel hyperglycosylated analog of recombinant human erythropoietin.
Toxicol Pathol
; 42(3): 540-54, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-23674392
3.
Pharmacokinetic and pharmacodynamic modeling of romiplostim in animals.
Pharm Res
; 30(3): 655-69, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23250851
4.
Investigation of the pharmacokinetics of romiplostim in rodents with a focus on the clearance mechanism.
Pharm Res
; 28(8): 1931-8, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21476045
5.
Clinical Pharmacokinetics and Pharmacodynamics of Etelcalcetide, a Novel Calcimimetic for Treatment of Secondary Hyperparathyroidism in Patients With Chronic Kidney Disease on Hemodialysis.
J Clin Pharmacol
; 58(6): 717-726, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29534286
6.
Clinical immunogenicity of the d-amino acid peptide therapeutic etelcalcetide: Method development challenges and anti-drug antibody clinical impact assessments.
J Immunol Methods
; 445: 37-44, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28274835
7.
Pharmacokinetics, Biotransformation, and Excretion of [14C]Etelcalcetide (AMG 416) Following a Single Microtracer Intravenous Dose in Patients with Chronic Kidney Disease on Hemodialysis.
Clin Pharmacokinet
; 56(2): 179-192, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27517676
8.
Experimental and statistical approaches in method cross-validation to support pharmacokinetic decisions.
J Pharm Biomed Anal
; 49(3): 613-8, 2009 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-19150189