Detalhe da pesquisa
1.
Activity and Expression of Carboxylesterases and Arylacetamide Deacetylase in Human Ocular Tissues.
Drug Metab Dispos
; 50(12): 1483-1492, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36195336
2.
Negative Regulation of Human Hepatic Constitutive Androstane Receptor by Cholesterol Synthesis Inhibition: Role of Sterol Regulatory Element Binding Proteins.
Drug Metab Dispos
; 49(8): 706-717, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34011532
3.
Carboxylesterase Activities and Protein Expression in Rabbit and Pig Ocular Tissues.
Mol Pharm
; 18(3): 1305-1316, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33595329
4.
Antiretroviral Penetration and Drug Transporter Concentrations in the Spleens of Three Preclinical Animal Models and Humans.
Antimicrob Agents Chemother
; 64(10)2020 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32661005
5.
Pharmacokinetics of Organic Cation Transporter 1 (OCT1) Substrates in Oct1/2 Knockout Mice and Species Difference in Hepatic OCT1-Mediated Uptake.
Drug Metab Dispos
; 48(2): 93-105, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31771949
6.
Antiretroviral Drug Concentrations in Lymph Nodes: A Cross-Species Comparison of the Effect of Drug Transporter Expression, Viral Infection, and Sex in Humanized Mice, Nonhuman Primates, and Humans.
J Pharmacol Exp Ther
; 370(3): 360-368, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31235531
7.
Developmental Expression of the Cytosolic Sulfotransferases in Human Liver.
Drug Metab Dispos
; 47(6): 592-600, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30885913
8.
Factors Affecting Interindividual Variability of Hepatic UGT2B17 Protein Expression Examined Using a Novel Specific Monoclonal Antibody.
Drug Metab Dispos
; 47(5): 444-452, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30819787
9.
A Monolayer of Primary Colonic Epithelium Generated on a Scaffold with a Gradient of Stiffness for Drug Transport Studies.
Anal Chem
; 90(22): 13331-13340, 2018 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30350627
10.
Efflux transporter breast cancer resistance protein dominantly expresses on the membrane of red blood cells, hinders partitioning of its substrates into the cells, and alters drug-drug interaction profiles.
Xenobiotica
; 48(11): 1173-1183, 2018 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-29098941
11.
Quantitative Characterization of Major Hepatic UDP-Glucuronosyltransferase Enzymes in Human Liver Microsomes: Comparison of Two Proteomic Methods and Correlation with Catalytic Activity.
Drug Metab Dispos
; 45(10): 1102-1112, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28768682
12.
Procedural outcomes of fluoroless catheter ablation outside the traditional catheterization lab.
Europace
; 19(8): 1378-1384, 2017 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27915262
13.
Scaling factors for the in vitro-in vivo extrapolation (IV-IVE) of renal drug and xenobiotic glucuronidation clearance.
Br J Clin Pharmacol
; 81(6): 1153-64, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26808419
14.
Quantification of Four Efflux Drug Transporters in Liver and Kidney Across Species Using Targeted Quantitative Proteomics by Isotope Dilution NanoLC-MS/MS.
Pharm Res
; 33(9): 2280-8, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27356525
15.
Multiplexed Targeted Quantitative Proteomics Predicts Hepatic Glucuronidation Potential.
Drug Metab Dispos
; 43(9): 1331-5, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26076694
16.
Quantitative profiling of human renal UDP-glucuronosyltransferases and glucuronidation activity: a comparison of normal and tumoral kidney tissues.
Drug Metab Dispos
; 43(4): 611-9, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25650382
17.
Utility of Oatp1a/1b-knockout and OATP1B1/3-humanized mice in the study of OATP-mediated pharmacokinetics and tissue distribution: case studies with pravastatin, atorvastatin, simvastatin, and carboxydichlorofluorescein.
Drug Metab Dispos
; 42(1): 182-92, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24194513
18.
Targeted quantitative proteomics for the analysis of 14 UGT1As and -2Bs in human liver using NanoUPLC-MS/MS with selected reaction monitoring.
J Proteome Res
; 12(10): 4402-13, 2013 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-23977844
19.
Targeted precise quantification of 12 human recombinant uridine-diphosphate glucuronosyl transferase 1A and 2B isoforms using nano-ultra-high-performance liquid chromatography/tandem mass spectrometry with selected reaction monitoring.
Drug Metab Dispos
; 41(12): 2076-80, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24046331
20.
Formation of CYP3A-specific metabolites of ibrutinib in vitro is correlated with hepatic CYP3A activity and 4ß-hydroxycholesterol/cholesterol ratio.
Clin Transl Sci
; 16(2): 279-291, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36350327