Detalhe da pesquisa
1.
Cell-to-cell heterogeneity in ion channel conductance impacts substrate vulnerability to arrhythmia.
Am J Physiol Heart Circ Physiol
; 2024 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38758124
2.
Prediction of arrhythmia susceptibility through mathematical modeling and machine learning.
Proc Natl Acad Sci U S A
; 118(37)2021 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34493665
3.
Protein structure-based gene expression signatures.
Proc Natl Acad Sci U S A
; 118(19)2021 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33941686
4.
Coupling and heterogeneity modulate pacemaking capability in healthy and diseased two-dimensional sinoatrial node tissue models.
PLoS Comput Biol
; 18(11): e1010098, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36409762
5.
The role of ß-adrenergic system remodeling in human heart failure: A mechanistic investigation.
J Mol Cell Cardiol
; 153: 14-25, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33326834
6.
Quantitative analysis of variability in an integrated model of human ventricular electrophysiology and ß-adrenergic signaling.
J Mol Cell Cardiol
; 143: 96-106, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32330487
7.
A distinct molecular mechanism by which phenytoin rescues a novel long QT 3 variant.
J Mol Cell Cardiol
; 144: 1-11, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32339567
8.
Experimental and Computational Insight Into Human Mesenchymal Stem Cell Paracrine Signaling and Heterocellular Coupling Effects on Cardiac Contractility and Arrhythmogenicity.
Circ Res
; 121(4): 411-423, 2017 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28642329
9.
A network medicine approach to build a comprehensive atlas for the prognosis of human cancer.
Brief Bioinform
; 17(6): 1044-1059, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27559151
10.
Differential roles of two delayed rectifier potassium currents in regulation of ventricular action potential duration and arrhythmia susceptibility.
J Physiol
; 595(7): 2301-2317, 2017 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27779762
11.
Cross-regulation of Phosphodiesterase 1 and Phosphodiesterase 2 Activities Controls Dopamine-mediated Striatal α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Trafficking.
J Biol Chem
; 291(44): 23257-23267, 2016 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27605670
12.
Modeling Electrophysiological Coupling and Fusion between Human Mesenchymal Stem Cells and Cardiomyocytes.
PLoS Comput Biol
; 12(7): e1005014, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27454812
13.
There and back again: Iterating between population-based modeling and experiments reveals surprising regulation of calcium transients in rat cardiac myocytes.
J Mol Cell Cardiol
; 96: 38-48, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26235057
14.
Improving cardiomyocyte model fidelity and utility via dynamic electrophysiology protocols and optimization algorithms.
J Physiol
; 594(9): 2525-36, 2016 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26661516
15.
Pathogenesis of the Novel Autoimmune-Associated Long-QT Syndrome.
Circulation
; 132(4): 230-40, 2015 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25995318
16.
Maximal acceleration of Ca2+ release refractoriness by ß-adrenergic stimulation requires dual activation of kinases PKA and CaMKII in mouse ventricular myocytes.
J Physiol
; 593(6): 1495-507, 2015 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25772298
17.
Na+ channel function, regulation, structure, trafficking and sequestration.
J Physiol
; 593(6): 1347-60, 2015 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25772290
18.
Calcium homeostasis in a local/global whole cell model of permeabilized ventricular myocytes with a Langevin description of stochastic calcium release.
Am J Physiol Heart Circ Physiol
; 308(5): H510-23, 2015 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25485896
19.
Comprehensive analyses of ventricular myocyte models identify targets exhibiting favorable rate dependence.
PLoS Comput Biol
; 10(3): e1003543, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24675446
20.
Creating cell-specific computational models of stem cell-derived cardiomyocytes using optical experiments.
bioRxiv
; 2024 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38260376