Detalhe da pesquisa
1.
The pioneer transcription factors Foxa1 and Foxa2 regulate alternative RNA splicing during thymocyte positive selection.
Development
; 148(15)2021 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34323272
2.
The transcriptional repressor Bcl6 promotes pre-TCR-induced thymocyte differentiation and attenuates Notch1 activation.
Development
; 147(19)2020 10 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32907850
3.
Gli3 in fetal thymic epithelial cells promotes thymocyte positive selection and differentiation by repression of Shh.
Development
; 145(3)2018 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-29361554
4.
IFITM proteins drive type 2 T helper cell differentiation and exacerbate allergic airway inflammation.
Eur J Immunol
; 49(1): 66-78, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30365177
5.
Foxa1 and Foxa2 in thymic epithelial cells (TEC) regulate medullary TEC and regulatory T-cell maturation.
J Autoimmun
; 93: 131-138, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30061015
6.
The transcriptional activator Gli2 modulates T-cell receptor signalling through attenuation of AP-1 and NFκB activity.
J Cell Sci
; 128(11): 2085-95, 2015 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25908851
7.
Sonic Hedgehog regulates thymic epithelial cell differentiation.
J Autoimmun
; 68: 86-97, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26778835
8.
The ATR inhibitor ceralasertib potentiates cancer checkpoint immunotherapy by regulating the tumor microenvironment.
Nat Commun
; 15(1): 1700, 2024 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38402224
9.
A preclinical model of peripheral T-cell lymphoma GATA3 reveals DNA damage response pathway vulnerability.
EMBO Mol Med
; 14(6): e15816, 2022 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35510955
10.
Direct targeting of FOXP3 in Tregs with AZD8701, a novel antisense oligonucleotide to relieve immunosuppression in cancer.
J Immunother Cancer
; 10(4)2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35387780
11.
Discovery of Proteolysis-Targeting Chimera Molecules that Selectively Degrade the IRAK3 Pseudokinase.
J Med Chem
; 63(18): 10460-10473, 2020 09 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32803978
12.
Sonic Hedgehog Is a Determinant of γδ T-Cell Differentiation in the Thymus.
Front Immunol
; 10: 1629, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31379834
13.
Sonic Hedgehog signaling limits atopic dermatitis via Gli2-driven immune regulation.
J Clin Invest
; 129(8): 3153-3170, 2019 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31264977
14.
The kinesin motor protein Kif7 is required for T-cell development and normal MHC expression on thymic epithelial cells (TEC) in the thymus.
Oncotarget
; 8(15): 24163-24176, 2017 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28445929
15.
The transcription factor Gli3 promotes B cell development in fetal liver through repression of Shh.
J Exp Med
; 214(7): 2041-2058, 2017 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28533268
16.
Hedgehog Signalling in the Embryonic Mouse Thymus.
J Dev Biol
; 4(3): 22, 2016 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27504268
17.
A genome wide transcriptional model of the complex response to pre-TCR signalling during thymocyte differentiation.
Oncotarget
; 6(30): 28646-60, 2015 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26415229